Supramolecular hydrogelation via host-guest anion recognition: lamellar hydrogel materials for the release of cationic cargo

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F21%3A00545408" target="_blank" >RIV/61389013:_____/21:00545408 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14310/21:00123019

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/abs/pii/S2451929421003569?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S2451929421003569?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.chempr.2021.06.024" target="_blank" >10.1016/j.chempr.2021.06.024</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Supramolecular hydrogelation via host-guest anion recognition: lamellar hydrogel materials for the release of cationic cargo

Popis výsledku v původním jazyce

Hydrogelation triggered by host-guest anion recognition is difficult to achieve due to the challenging anion recognition in water and de novo gelator design. Herein, we report such a hydrogel system, based on bambus[6]uril anion receptor, BU. Albeit not a gelator per se, BU formed hydrogels selectively in the presence of iodides or perchlorates. Anion recognition by BU governed the hydrogelation, indicated by the NMR, ATR-IR, and single-crystal X-ray. Gelation mechanism and lamellar nature of the network structure were elucidated by SAXS, cryoSEM, and holotomography methods. Rheological characterization revealed the hydrogels were stable and relatively strong. In physiological saline solutions, the hydrogels released cationic cargo by cation metathesis, leading to a gel-to-gel transformation. Choline derivatives, as model drugs, exhibited slow release from the hydrogels. Our simple hydrogel system may inspire the design of smart materials based on host-guest anion recognition, where the release or sequestration of specific charged species are desirable.

Název v anglickém jazyce

Supramolecular hydrogelation via host-guest anion recognition: lamellar hydrogel materials for the release of cationic cargo

Popis výsledku anglicky

Hydrogelation triggered by host-guest anion recognition is difficult to achieve due to the challenging anion recognition in water and de novo gelator design. Herein, we report such a hydrogel system, based on bambus[6]uril anion receptor, BU. Albeit not a gelator per se, BU formed hydrogels selectively in the presence of iodides or perchlorates. Anion recognition by BU governed the hydrogelation, indicated by the NMR, ATR-IR, and single-crystal X-ray. Gelation mechanism and lamellar nature of the network structure were elucidated by SAXS, cryoSEM, and holotomography methods. Rheological characterization revealed the hydrogels were stable and relatively strong. In physiological saline solutions, the hydrogels released cationic cargo by cation metathesis, leading to a gel-to-gel transformation. Choline derivatives, as model drugs, exhibited slow release from the hydrogels. Our simple hydrogel system may inspire the design of smart materials based on host-guest anion recognition, where the release or sequestration of specific charged species are desirable.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

10404 - Polymer science

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Chem

ISSN

2451-9294

e-ISSN

2451-9294

Svazek periodika

7

Číslo periodika v rámci svazku

9

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

18

Strana od-do

2473-2490

Kód UT WoS článku

000695415900017

EID výsledku v databázi Scopus

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