GC/MS deterination of ibotenic acid and muscimol in the urine of patients intoxicated with Amanita pantherina.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F12%3A33140136" target="_blank" >RIV/61989592:15110/12:33140136 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61989592:15310/12:33140136

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00414-011-0599-9" target="_blank" >http://dx.doi.org/10.1007/s00414-011-0599-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00414-011-0599-9" target="_blank" >10.1007/s00414-011-0599-9</a>

Jazyk výsledku

angličtina

Název v původním jazyce

GC/MS deterination of ibotenic acid and muscimol in the urine of patients intoxicated with Amanita pantherina.

Popis výsledku v původním jazyce

Ibotenic acid and muscimol are substances which mostly participate in psychotropic properties of Amanita pantherina and Amanita muscaria. They are rapidly absorbed from the gastrointestinal tract and readily excreted in urien. The poisoning with A.pantherina is in the majority of cases accidental because it can be easily mistaken for the edible species. Intoxication with A.muscaria is ostly intentional for recreational purposes. Prognosis of the poisoning is generaly good; lethal cases are rare. Mushroom poisoning is often proved by microscopic examination of spores in the stomach or intestinal content. Authors of this article introduce an instrumental method of proving A.pantherina or A.muscaria poisoning. The article describes the isolation of ibotenic acid and muscimol form urine, the derivatization step and the determination of these compounds by gas chromatography/mass spectrometry. Isolation of these alkaloids from urine was performed on a strong cation exchanger, and the elution

Název v anglickém jazyce

GC/MS deterination of ibotenic acid and muscimol in the urine of patients intoxicated with Amanita pantherina.

Popis výsledku anglicky

Ibotenic acid and muscimol are substances which mostly participate in psychotropic properties of Amanita pantherina and Amanita muscaria. They are rapidly absorbed from the gastrointestinal tract and readily excreted in urien. The poisoning with A.pantherina is in the majority of cases accidental because it can be easily mistaken for the edible species. Intoxication with A.muscaria is ostly intentional for recreational purposes. Prognosis of the poisoning is generaly good; lethal cases are rare. Mushroom poisoning is often proved by microscopic examination of spores in the stomach or intestinal content. Authors of this article introduce an instrumental method of proving A.pantherina or A.muscaria poisoning. The article describes the isolation of ibotenic acid and muscimol form urine, the derivatization step and the determination of these compounds by gas chromatography/mass spectrometry. Isolation of these alkaloids from urine was performed on a strong cation exchanger, and the elution

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/NS10269" target="_blank" >NS10269: Objektivní analytická metoda k diagnostice intoxikací muchomůrkami</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2012

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

International Journal of Legal Medicine

ISSN

0937-9827

e-ISSN

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Svazek periodika

126

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

6

Strana od-do

519-524

Kód UT WoS článku

000305565400006

EID výsledku v databázi Scopus

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