Cerebrospinal fluid inflammatory markers in patients with multiple sclerosis: a pilot study.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F15%3A33155746" target="_blank" >RIV/61989592:15110/15:33155746 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00098892:_____/15:#0000950

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s00702-014-1244-9" target="_blank" >http://dx.doi.org/10.1007/s00702-014-1244-9</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s00702-014-1244-9" target="_blank" >10.1007/s00702-014-1244-9</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cerebrospinal fluid inflammatory markers in patients with multiple sclerosis: a pilot study.

Popis výsledku v původním jazyce

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. Autoimmune inflammation is common in the early stages of MS. This stage is followed by the neurodegenerative process. The result of these changes is axon andmyelin breakdown. Although MS is according to McDonald's revised diagnostic criteria primarily a clinical diagnosis, paraclinical investigation methods are an important part in the diagnosis of MS. In common practice, magnetic resonance imaging of the brain and spinal cord, examination of cerebrospinal fluid (CSF) and examination of visual evoked potentials are used. There are an increasing number of studies dealing with biomarkers in CSF and their role in the diagnosis and treatment of MS. We hypothesized that the levels of some markers could be changed in MS in comparison with controls. We studied five inflammatory markers [interleukin-6 (IL-6), interleukin-8, interleukin-10 (IL-10), beta-2-microglobulin, orosomucoid]. CSF and serum l

Název v anglickém jazyce

Cerebrospinal fluid inflammatory markers in patients with multiple sclerosis: a pilot study.

Popis výsledku anglicky

Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. Autoimmune inflammation is common in the early stages of MS. This stage is followed by the neurodegenerative process. The result of these changes is axon andmyelin breakdown. Although MS is according to McDonald's revised diagnostic criteria primarily a clinical diagnosis, paraclinical investigation methods are an important part in the diagnosis of MS. In common practice, magnetic resonance imaging of the brain and spinal cord, examination of cerebrospinal fluid (CSF) and examination of visual evoked potentials are used. There are an increasing number of studies dealing with biomarkers in CSF and their role in the diagnosis and treatment of MS. We hypothesized that the levels of some markers could be changed in MS in comparison with controls. We studied five inflammatory markers [interleukin-6 (IL-6), interleukin-8, interleukin-10 (IL-10), beta-2-microglobulin, orosomucoid]. CSF and serum l

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FH - Neurologie, neurochirurgie, neurovědy

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Neural Transmission

ISSN

0300-9564

e-ISSN

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Svazek periodika

2015

Číslo periodika v rámci svazku

122

Stát vydavatele periodika

AT - Rakouská republika

Počet stran výsledku

5

Strana od-do

273-277

Kód UT WoS článku

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EID výsledku v databázi Scopus

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