Identification of novel OXA-134-like beta-lactamases in Acinetobacter Iwoffii and Acinetobacter schindleri isolated from chicken litter

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F19%3A73599770" target="_blank" >RIV/61989592:15110/19:73599770 - isvavai.cz</a>

Výsledek na webu

<a href="https://biomed.papers.upol.cz/pdfs/bio/2019/02/06.pdf" target="_blank" >https://biomed.papers.upol.cz/pdfs/bio/2019/02/06.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2018.037" target="_blank" >10.5507/bp.2018.037</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Identification of novel OXA-134-like beta-lactamases in Acinetobacter Iwoffii and Acinetobacter schindleri isolated from chicken litter

Popis výsledku v původním jazyce

Background. Various food-producing animals have been recognized in recent years as a potential reservoir for the spread of antibiotic resistant bacteria that may pose a risk to human health and therefore their dissemination in the food production chain needs to be assessed. Methods. In this study, 450 boot swabs from chicken farms were analyzed for the presence of antimicrobial resistance with a focus on beta-lactams resistance in Acinetobacter species. Results. Two beta-lactamase-encoding genes were first time identified in Acinetobacter Iwoffii and Acinetobacter schindleri isolates.The deduced amino acid sequence of OXA-496 shared 93.8% identity with OXA-363. The second OXA-134-like enzyme, OXA-537, had the highest sequence identity (97.8%) with OXA-235 and OXA-237. Conclusions. The results of this study illustrate the occurrence of new OXA-134-like beta-lactamases, called OXA-496 and OXA-537, carrying strains of Acinetobacter Iwoffii and Acinetobacter schindleri in chicken farm litter, and highlight the possible role of Acinetobacter as a reservoir of resistance genes.

Název v anglickém jazyce

Identification of novel OXA-134-like beta-lactamases in Acinetobacter Iwoffii and Acinetobacter schindleri isolated from chicken litter

Popis výsledku anglicky

Background. Various food-producing animals have been recognized in recent years as a potential reservoir for the spread of antibiotic resistant bacteria that may pose a risk to human health and therefore their dissemination in the food production chain needs to be assessed. Methods. In this study, 450 boot swabs from chicken farms were analyzed for the presence of antimicrobial resistance with a focus on beta-lactams resistance in Acinetobacter species. Results. Two beta-lactamase-encoding genes were first time identified in Acinetobacter Iwoffii and Acinetobacter schindleri isolates.The deduced amino acid sequence of OXA-496 shared 93.8% identity with OXA-363. The second OXA-134-like enzyme, OXA-537, had the highest sequence identity (97.8%) with OXA-235 and OXA-237. Conclusions. The results of this study illustrate the occurrence of new OXA-134-like beta-lactamases, called OXA-496 and OXA-537, carrying strains of Acinetobacter Iwoffii and Acinetobacter schindleri in chicken farm litter, and highlight the possible role of Acinetobacter as a reservoir of resistance genes.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

10606 - Microbiology

Projekt

<a href="/cs/project/LO1304" target="_blank" >LO1304: Podpora udržitelnosti Ústavu molekulární a translační medicíny</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

BIOMEDICAL PAPERS-OLOMOUC

ISSN

1213-8118

e-ISSN

—

Svazek periodika

163

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

141-146

Kód UT WoS článku

000477957000006

EID výsledku v databázi Scopus

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