On GC/MS in phospholipid research II: Investigation of liposome formation and liposome-water partitioning

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F11%3A33118053" target="_blank" >RIV/61989592:15310/11:33118053 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

On GC/MS in phospholipid research II: Investigation of liposome formation and liposome-water partitioning

Popis výsledku v původním jazyce

Headspace solid phase microextraction gas chromatography / mass spectrometry was used for determination of critical liposome concentration of soybean phospholipid (asolectin) and liposome water partition coefficient of eugenol. Constant amount of eugenolwas incubated with constant volume of asolectin solutions for 12 hours. Peak area corresponding to the eugenol concentration in the headspace and thus to the fraction of free eugenol was recorded in dependence on asolectin concentration. The initial andterminal parts of the experimental dependence were extrapolated with two straight lines whose intersection corresponds to the concentration value (1.097 g/l) remarkably conformable to the value of critical liposome concentration obtained from cyclic voltammetry (1.126 g/l). Liposom water partition coefficient was determined from the measured concentration of free eugenol and known volume of the liposomal phase. Partition coefficient values 300, 297 and 305 were obtained in solutions wit

Název v anglickém jazyce

On GC/MS in phospholipid research II: Investigation of liposome formation and liposome-water partitioning

Popis výsledku anglicky

Headspace solid phase microextraction gas chromatography / mass spectrometry was used for determination of critical liposome concentration of soybean phospholipid (asolectin) and liposome water partition coefficient of eugenol. Constant amount of eugenolwas incubated with constant volume of asolectin solutions for 12 hours. Peak area corresponding to the eugenol concentration in the headspace and thus to the fraction of free eugenol was recorded in dependence on asolectin concentration. The initial andterminal parts of the experimental dependence were extrapolated with two straight lines whose intersection corresponds to the concentration value (1.097 g/l) remarkably conformable to the value of critical liposome concentration obtained from cyclic voltammetry (1.126 g/l). Liposom water partition coefficient was determined from the measured concentration of free eugenol and known volume of the liposomal phase. Partition coefficient values 300, 297 and 305 were obtained in solutions wit

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/ED2.1.00%2F03.0058" target="_blank" >ED2.1.00/03.0058: Regionální centrum pokročilých technologií a materiálů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Acta Universitatis Palackianae Olomucensis, Facultas Rerum Naturalium, Chemica

ISSN

0232-0061

e-ISSN

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Svazek periodika

48

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

6

Strana od-do

8-13

Kód UT WoS článku

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EID výsledku v databázi Scopus

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