BIOSPEAN: A freeware tool for processing spectra from MALDI intact cell/spore mass spectrometry

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F13%3A33147897" target="_blank" >RIV/61989592:15310/13:33147897 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.4172/jpb.1000292" target="_blank" >http://dx.doi.org/10.4172/jpb.1000292</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4172/jpb.1000292" target="_blank" >10.4172/jpb.1000292</a>

Jazyk výsledku

angličtina

Název v původním jazyce

BIOSPEAN: A freeware tool for processing spectra from MALDI intact cell/spore mass spectrometry

Popis výsledku v původním jazyce

Here we introduce the software BIOSPEAN, which is applicable for processing of peptide/protein profiles obtained from MALDI intact cell/spore mass spectrometry. It has been developed as a web application using common technology. The BIOSPEAN automatically finds peaks in a mass spectrum. The peak detection principle involves a local scanning of intensity values around individual m/z positions. To cope with the level of noise, a threshold signal-to-noise ratio is adjusted for filtering relevant results. Based on the detected peak pattern, a similarity search in a custom spectral database can subsequently be performed for sample identification. When a spectrum is analyzed by comparison with a database entry, a percentage score value is calculated from thenumber of identical peak positions found (they are assigned with an adjustable mass tolerance) divided by the number of all detected peaks in the analyzed spectrum. Each two spectra may also be compared in the opposite way and both score

Název v anglickém jazyce

BIOSPEAN: A freeware tool for processing spectra from MALDI intact cell/spore mass spectrometry

Popis výsledku anglicky

Here we introduce the software BIOSPEAN, which is applicable for processing of peptide/protein profiles obtained from MALDI intact cell/spore mass spectrometry. It has been developed as a web application using common technology. The BIOSPEAN automatically finds peaks in a mass spectrum. The peak detection principle involves a local scanning of intensity values around individual m/z positions. To cope with the level of noise, a threshold signal-to-noise ratio is adjusted for filtering relevant results. Based on the detected peak pattern, a similarity search in a custom spectral database can subsequently be performed for sample identification. When a spectrum is analyzed by comparison with a database entry, a percentage score value is calculated from thenumber of identical peak positions found (they are assigned with an adjustable mass tolerance) divided by the number of all detected peaks in the analyzed spectrum. Each two spectra may also be compared in the opposite way and both score

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CE - Biochemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Proteomics and Bioinformatics

ISSN

0974-276X

e-ISSN

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Svazek periodika

6

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

283-287

Kód UT WoS článku

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EID výsledku v databázi Scopus

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