Chestnut shells (Italian cultivar "Marrone di Roccadaspide" PGI): Antioxidant activity and chemical investigation with in depth LC-HRMS/MSn rationalization of tannins

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F20%3A73604546" target="_blank" >RIV/61989592:15310/20:73604546 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0963996919306738" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0963996919306738</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.foodres.2019.108787" target="_blank" >10.1016/j.foodres.2019.108787</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Chestnut shells (Italian cultivar "Marrone di Roccadaspide" PGI): Antioxidant activity and chemical investigation with in depth LC-HRMS/MSn rationalization of tannins

Popis výsledku v původním jazyce

In Italy a particularly valuable chestnut is &quot;Man-one di Roccadaspide&quot;, a protected geographical indication (PGI) product, deriving from a Castanea saliva cultivar, typical of Salerno province in Campania region. As chestnut industrial processes yield a large amount of shell by-products, in this study the possibility to retrain this waste food as potential source of bioactives was investigated. The ability of &quot;Marrone di Roccadaspide&quot; shell MeOH extract to modulate the pro-inflammatory transcriptional factor NF-kappa B after LPS stimulation, along with the antioxidant activity by a cell-based in vitro test, were evaluated. To correlate the NF-kappa B inhibition (67.67% at 5 mu g/mL) and the strong antioxidant activity to the chemical composition, an analytical approach based on LCESI/LTQOrbitrap/MS/MS&quot; along with NMR characterization of isolated compounds was developed. The identification of hydrolysable and condensed tannins, along with flavonoids, phenol glucosides, ellagic acid derivatives, and triterpenoids was accomplished. The most representative compounds were quantitatively analyzed by LC-ESI/QTrap/MS/MS, showing bartogenic acid as the compound occurring in the highest amount (103.08 mg/100 g shells). With the aim to explore the possibility to employ chestnut shells as suitable source of bioactives for the preparation of functional ingredients, the chemical composition and the antioxidant activity of &quot;eco-friendly&quot; extracts (EtOH and EtOH:H2O 7:3) was finally evaluated, showing a high superimposability of the EtOH:H2O (7:3) extract to the MeOH extract.

Název v anglickém jazyce

Chestnut shells (Italian cultivar "Marrone di Roccadaspide" PGI): Antioxidant activity and chemical investigation with in depth LC-HRMS/MSn rationalization of tannins

Popis výsledku anglicky

In Italy a particularly valuable chestnut is &quot;Man-one di Roccadaspide&quot;, a protected geographical indication (PGI) product, deriving from a Castanea saliva cultivar, typical of Salerno province in Campania region. As chestnut industrial processes yield a large amount of shell by-products, in this study the possibility to retrain this waste food as potential source of bioactives was investigated. The ability of &quot;Marrone di Roccadaspide&quot; shell MeOH extract to modulate the pro-inflammatory transcriptional factor NF-kappa B after LPS stimulation, along with the antioxidant activity by a cell-based in vitro test, were evaluated. To correlate the NF-kappa B inhibition (67.67% at 5 mu g/mL) and the strong antioxidant activity to the chemical composition, an analytical approach based on LCESI/LTQOrbitrap/MS/MS&quot; along with NMR characterization of isolated compounds was developed. The identification of hydrolysable and condensed tannins, along with flavonoids, phenol glucosides, ellagic acid derivatives, and triterpenoids was accomplished. The most representative compounds were quantitatively analyzed by LC-ESI/QTrap/MS/MS, showing bartogenic acid as the compound occurring in the highest amount (103.08 mg/100 g shells). With the aim to explore the possibility to employ chestnut shells as suitable source of bioactives for the preparation of functional ingredients, the chemical composition and the antioxidant activity of &quot;eco-friendly&quot; extracts (EtOH and EtOH:H2O 7:3) was finally evaluated, showing a high superimposability of the EtOH:H2O (7:3) extract to the MeOH extract.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30104 - Pharmacology and pharmacy

Projekt

<a href="/cs/project/LO1305" target="_blank" >LO1305: Rozvoj centra pokročilých technologií a materiálů</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

FOOD RESEARCH INTERNATIONAL

ISSN

0963-9969

e-ISSN

—

Svazek periodika

129

Číslo periodika v rámci svazku

MAR

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

14

Strana od-do

"108787-1"-"108787-14"

Kód UT WoS článku

000517665500010

EID výsledku v databázi Scopus

2-s2.0-85075854215