Biocompatibility and mechanical properties of pigeon bone waste extracted natural nano-hydroxyapatite for bone tissue engineering

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15640%2F21%3A73609188" target="_blank" >RIV/61989592:15640/21:73609188 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0921510720304578?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0921510720304578?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.mseb.2020.114950" target="_blank" >10.1016/j.mseb.2020.114950</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Biocompatibility and mechanical properties of pigeon bone waste extracted natural nano-hydroxyapatite for bone tissue engineering

Popis výsledku v původním jazyce

One of the common bioactive materials used for clinical and biomedical applications is hydroxyapatite (HAp). Bio-waste materials are one of the major natural sources for the preparation of this bio-ceramic powder. Herein, naturally derived nano-HAp was prepared using the ball milling process after annealing of waste pigeon bones at 850 °C followed by cold-pressing the nanoparticles and re-sintering at 850, 950, 1050, and 1150 °C. The ball-milled pigeon-derived nano-hydroxyapatite (PHA) had an average particle size in the range of 50–250 nm and the Ca/P ratio of the sample sintered at 1050 °C was 1.7. Moreover, the hardness and compressive strength of sintered nano-HAp were improved to 47.57 MPa and 3.7 GPa, respectively by increasing the sintering temperature. Furthermore, alkaline phosphatase analysis and MTT assay of PHA indicated significant enhancement in the activity and proliferation of osteoblast cells during the culturing period in comparison to synthetic HAp.

Název v anglickém jazyce

Biocompatibility and mechanical properties of pigeon bone waste extracted natural nano-hydroxyapatite for bone tissue engineering

Popis výsledku anglicky

One of the common bioactive materials used for clinical and biomedical applications is hydroxyapatite (HAp). Bio-waste materials are one of the major natural sources for the preparation of this bio-ceramic powder. Herein, naturally derived nano-HAp was prepared using the ball milling process after annealing of waste pigeon bones at 850 °C followed by cold-pressing the nanoparticles and re-sintering at 850, 950, 1050, and 1150 °C. The ball-milled pigeon-derived nano-hydroxyapatite (PHA) had an average particle size in the range of 50–250 nm and the Ca/P ratio of the sample sintered at 1050 °C was 1.7. Moreover, the hardness and compressive strength of sintered nano-HAp were improved to 47.57 MPa and 3.7 GPa, respectively by increasing the sintering temperature. Furthermore, alkaline phosphatase analysis and MTT assay of PHA indicated significant enhancement in the activity and proliferation of osteoblast cells during the culturing period in comparison to synthetic HAp.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

21001 - Nano-materials (production and properties)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materials Science and Engineering B-Advanced Functional Solid-State Materials

ISSN

0921-5107

e-ISSN

—

Svazek periodika

2021

Číslo periodika v rámci svazku

264

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

7

Strana od-do

"nečíslováno"

Kód UT WoS článku

000605207500004

EID výsledku v databázi Scopus

2-s2.0-85097877361