Physical, mechanical, and biological properties of electrophoretically deposited lithium-doped calcium phosphates

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081723%3A_____%2F18%3A00491339" target="_blank" >RIV/68081723:_____/18:00491339 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216305:26620/18:PU125910

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ceramint.2017.11.035" target="_blank" >http://dx.doi.org/10.1016/j.ceramint.2017.11.035</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ceramint.2017.11.035" target="_blank" >10.1016/j.ceramint.2017.11.035</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Physical, mechanical, and biological properties of electrophoretically deposited lithium-doped calcium phosphates

Popis výsledku v původním jazyce

In the present work, the preparation of sintered lithium-doped tricalcium phosphates was studied, along with their physical, mechanical, and biological properties. Calcium phosphates were shaped via the use of electrophoretic deposition (EPD), using colloidally milled dispersions of hydroxyapatite (HAp) particles. The dispersions were stabilised with monochloroacetic acid. Lithium was incorporated into the structure via an addition of lithium chloride, which also served to optimise the deposition process. The dispersions were milled colloidally for periods of 0-48 h. The colloidal milling resulted in two effects: i) disintegration of the commercial HAp powder (10 mu m) agglomerates, ii) unimodal distribution of the HAp particles ( similar to 170 nm). The fine particles of the milled HAp dispersions accelerated the deposition rate, and increased the mass of the deposit. The reduced size of the initial particles, owed to the milling, led to the superior arrangement of the particles during deposition and to reduced porosity after sintering (1050-1250 degrees C). The HAp decomposed into tricalcium phosphate phases during sintering. At a sintering temperature of 1250 degrees C, grain growth occurred, which consequently resulted in a slight degradation of the mechanical properties (reduction in hardness and Young's modulus). In contrast, the hardness and Young's modulus increased as the dispersion milling time increased (smaller grain size after sintering), however, the fracture toughness did not change. The results of the biological testing confirmed the bioactivity of the material through the growth of the apatite layer in the simulated body fluid (SBF), and the biodegradation of the prepared materials in the Tris-HCI solution. With regard to the preparation of compact lithium-doped tricalcium phosphates, the best results were obtained in the case of the sample that utilised the dispersion that was milled for 48 h, and was sintered at 1050 degrees C.

Název v anglickém jazyce

Physical, mechanical, and biological properties of electrophoretically deposited lithium-doped calcium phosphates

Popis výsledku anglicky

In the present work, the preparation of sintered lithium-doped tricalcium phosphates was studied, along with their physical, mechanical, and biological properties. Calcium phosphates were shaped via the use of electrophoretic deposition (EPD), using colloidally milled dispersions of hydroxyapatite (HAp) particles. The dispersions were stabilised with monochloroacetic acid. Lithium was incorporated into the structure via an addition of lithium chloride, which also served to optimise the deposition process. The dispersions were milled colloidally for periods of 0-48 h. The colloidal milling resulted in two effects: i) disintegration of the commercial HAp powder (10 mu m) agglomerates, ii) unimodal distribution of the HAp particles ( similar to 170 nm). The fine particles of the milled HAp dispersions accelerated the deposition rate, and increased the mass of the deposit. The reduced size of the initial particles, owed to the milling, led to the superior arrangement of the particles during deposition and to reduced porosity after sintering (1050-1250 degrees C). The HAp decomposed into tricalcium phosphate phases during sintering. At a sintering temperature of 1250 degrees C, grain growth occurred, which consequently resulted in a slight degradation of the mechanical properties (reduction in hardness and Young's modulus). In contrast, the hardness and Young's modulus increased as the dispersion milling time increased (smaller grain size after sintering), however, the fracture toughness did not change. The results of the biological testing confirmed the bioactivity of the material through the growth of the apatite layer in the simulated body fluid (SBF), and the biodegradation of the prepared materials in the Tris-HCI solution. With regard to the preparation of compact lithium-doped tricalcium phosphates, the best results were obtained in the case of the sample that utilised the dispersion that was milled for 48 h, and was sintered at 1050 degrees C.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20504 - Ceramics

Projekt

<a href="/cs/project/LD14072" target="_blank" >LD14072: Funkčně a strukturně gradientní biokompozity a skafoldy na bázi Ca-fosfátů pro kostní tkáňové inženýrství</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Ceramics International

ISSN

0272-8842

e-ISSN

—

Svazek periodika

44

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

2884-2891

Kód UT WoS článku

000423891900034

EID výsledku v databázi Scopus

2-s2.0-85033781770