The effect of amaranth flour on plasma lipids profile in mice with diet-induced dyslipidaemia.

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F13%3A43871789" target="_blank" >RIV/62157124:16370/13:43871789 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

The effect of amaranth flour on plasma lipids profile in mice with diet-induced dyslipidaemia.

Popis výsledku v původním jazyce

The present study was designated to investigate the effect of amaranth flour on plasma lipids profile in mice with dietary induced dyslipidemia. 50 inbred mice, males, were randomly assigned into 5 groups. Individual groups were on different diets during49 days: Control diet (C group), high energy diet (HED), high energy diet with amaranth flour (HED+A), high energy diet with amaranth flour and simvastatin (HED+A+S), and high energy diet with simvastatin (HED+S). Addition of cholesterol and sugar (glucose) to the diet resulted in significant increase of total (TOT-C) and low-density lipoproteins cholesterol (LDL-C) with concomitant decrease of high density lipoproteins cholesterol (HDL-C) in HED group. Addition of amaranth into the feed mixture resulted in the decrease of TOT-C levels by 41% (P{0.05) and LDL-C levels by 50% (P{0.05) in HED+A group. Similar effect was observed in the HED+A+S group where TOT-C decreased by 37% (P{0.05) and LDL-C by 54% (P{0.05). Addition of amaranth int

Název v anglickém jazyce

The effect of amaranth flour on plasma lipids profile in mice with diet-induced dyslipidaemia.

Popis výsledku anglicky

The present study was designated to investigate the effect of amaranth flour on plasma lipids profile in mice with dietary induced dyslipidemia. 50 inbred mice, males, were randomly assigned into 5 groups. Individual groups were on different diets during49 days: Control diet (C group), high energy diet (HED), high energy diet with amaranth flour (HED+A), high energy diet with amaranth flour and simvastatin (HED+A+S), and high energy diet with simvastatin (HED+S). Addition of cholesterol and sugar (glucose) to the diet resulted in significant increase of total (TOT-C) and low-density lipoproteins cholesterol (LDL-C) with concomitant decrease of high density lipoproteins cholesterol (HDL-C) in HED group. Addition of amaranth into the feed mixture resulted in the decrease of TOT-C levels by 41% (P{0.05) and LDL-C levels by 50% (P{0.05) in HED+A group. Similar effect was observed in the HED+A+S group where TOT-C decreased by 37% (P{0.05) and LDL-C by 54% (P{0.05). Addition of amaranth int

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2013

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Current Topics in Nutraceutical Research

ISSN

1540-7535

e-ISSN

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Svazek periodika

11

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

67-74

Kód UT WoS článku

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EID výsledku v databázi Scopus

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