Cytotoxic potential of C-prenylated flavonoids

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16370%2F14%3A43872372" target="_blank" >RIV/62157124:16370/14:43872372 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1007/s11101-013-9308-2" target="_blank" >http://dx.doi.org/10.1007/s11101-013-9308-2</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11101-013-9308-2" target="_blank" >10.1007/s11101-013-9308-2</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Cytotoxic potential of C-prenylated flavonoids

Popis výsledku v původním jazyce

Prenylated flavonoids are a large group of compounds that combine a flavonoid skeleton with a lipophilic prenyl side-chain. The-side chain may be modified, especially by oxidation, and this variation contributes many structural possibilities. Combining the flavonoid skeleton with a lipophilicity of the prenyl side-chain gives the resultant great potential for biological activity. The cytotoxic activity of prenylated flavonoids has been reviewed with the aim of evaluating the potential of these compoundsfor further research. The search for activity has been restricted to from blood derived cells to limit the number of sources cited and get a more valuable comparison of the compounds. All sources touching on the potential toxicity of prenylated flavonoids on blood-cell lines in last 30 years of research have been cited in this review. The Sciencedirect, Web of Knowledge, Scifinder, and Reaxys databases were searched for reports, descriptions, and structural information prenylated flavon

Název v anglickém jazyce

Cytotoxic potential of C-prenylated flavonoids

Popis výsledku anglicky

Prenylated flavonoids are a large group of compounds that combine a flavonoid skeleton with a lipophilic prenyl side-chain. The-side chain may be modified, especially by oxidation, and this variation contributes many structural possibilities. Combining the flavonoid skeleton with a lipophilicity of the prenyl side-chain gives the resultant great potential for biological activity. The cytotoxic activity of prenylated flavonoids has been reviewed with the aim of evaluating the potential of these compoundsfor further research. The search for activity has been restricted to from blood derived cells to limit the number of sources cited and get a more valuable comparison of the compounds. All sources touching on the potential toxicity of prenylated flavonoids on blood-cell lines in last 30 years of research have been cited in this review. The Sciencedirect, Web of Knowledge, Scifinder, and Reaxys databases were searched for reports, descriptions, and structural information prenylated flavon

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FR - Farmakologie a lékárnická chemie

OECD FORD obor

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Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Phytochemistry Reviews

ISSN

1568-7767

e-ISSN

—

Svazek periodika

13

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

31

Strana od-do

245-275

Kód UT WoS článku

000331818000016

EID výsledku v databázi Scopus

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