Complexity-based analysis of the alterations in the structure of coronaviruses

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18450%2F21%3A50017973" target="_blank" >RIV/62690094:18450/21:50017973 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.worldscientific.com/doi/abs/10.1142/S0218348X21501231" target="_blank" >https://www.worldscientific.com/doi/abs/10.1142/S0218348X21501231</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1142/S0218348X21501231" target="_blank" >10.1142/S0218348X21501231</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Complexity-based analysis of the alterations in the structure of coronaviruses

Popis výsledku v původním jazyce

The coronavirus has influenced the lives of many people since its identification in 1960. In general, there are seven types of coronavirus. Although some types of this virus, including 229E, NL63, OC43, and HKU1, cause mild to moderate illness, SARS-CoV, MERS-CoV, and SARS-CoV-2 have shown to have severer effects on the human body. Specifically, the recent known type of coronavirus, SARS-CoV-2, has affected the lives of many people around the world since late 2019 with the disease named COVID-19. In this paper, for the first time, we investigated the variations among the complex structures of coronaviruses. We employed the fractal dimension, approximate entropy, and sample entropy as the measures of complexity. Based on the obtained results, SARS-CoV-2 has a significantly different complex structure than SARS-CoV and MERS-CoV. To study the high mutation rate of SARS-CoV-2, we also analyzed the long-term memory of genome walks for different coronaviruses using the Hurst exponent. The results demonstrated that the SARS-CoV-2 shows the lowest memory in its genome walk, explaining the errors in copying the sequences along the genome that results in the virus mutation. © 2021 The Author(s). The Author(s).

Název v anglickém jazyce

Complexity-based analysis of the alterations in the structure of coronaviruses

Popis výsledku anglicky

The coronavirus has influenced the lives of many people since its identification in 1960. In general, there are seven types of coronavirus. Although some types of this virus, including 229E, NL63, OC43, and HKU1, cause mild to moderate illness, SARS-CoV, MERS-CoV, and SARS-CoV-2 have shown to have severer effects on the human body. Specifically, the recent known type of coronavirus, SARS-CoV-2, has affected the lives of many people around the world since late 2019 with the disease named COVID-19. In this paper, for the first time, we investigated the variations among the complex structures of coronaviruses. We employed the fractal dimension, approximate entropy, and sample entropy as the measures of complexity. Based on the obtained results, SARS-CoV-2 has a significantly different complex structure than SARS-CoV and MERS-CoV. To study the high mutation rate of SARS-CoV-2, we also analyzed the long-term memory of genome walks for different coronaviruses using the Hurst exponent. The results demonstrated that the SARS-CoV-2 shows the lowest memory in its genome walk, explaining the errors in copying the sequences along the genome that results in the virus mutation. © 2021 The Author(s). The Author(s).

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10102 - Applied mathematics

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Fractals

ISSN

0218-348X

e-ISSN

—

Svazek periodika

29

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

SG - Singapurská republika

Počet stran výsledku

11

Strana od-do

"Article number 2150123"

Kód UT WoS článku

000641993400031

EID výsledku v databázi Scopus

2-s2.0-85103023692