Synthesis and Biological Activity of Hydrazones and Derivatives: A Review

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F20%3A50021373" target="_blank" >RIV/62690094:18470/20:50021373 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.eurekaselect.com/article/101419" target="_blank" >https://www.eurekaselect.com/article/101419</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2174/1389557519666191014142448" target="_blank" >10.2174/1389557519666191014142448</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Synthesis and Biological Activity of Hydrazones and Derivatives: A Review

Popis výsledku v původním jazyce

Hydrazones and their derivatives are very important compounds in medicinal chemistry due to their reported biological activity for the treatment of several diseases, like Alzheimer&apos;s, cancer, inflammation, and leishmaniasis. However, most of the investigations on hydrazones available in literature today are directed to the synthesis of these molecules with little discussion available on their biological activities. With the purpose of bringing lights into this issue, we performed a revision of the literature and wrote this review based on some of the most current research reports of hydrazones and derivatives, making it clear that the synthesis of these molecules can lead to new drug prototypes. Our goal is to encourage more studies focused on the synthesis and evaluation of new hydrazones, as a contribution to the development of potential new drugs for the treatment of various diseases.

Název v anglickém jazyce

Synthesis and Biological Activity of Hydrazones and Derivatives: A Review

Popis výsledku anglicky

Hydrazones and their derivatives are very important compounds in medicinal chemistry due to their reported biological activity for the treatment of several diseases, like Alzheimer&apos;s, cancer, inflammation, and leishmaniasis. However, most of the investigations on hydrazones available in literature today are directed to the synthesis of these molecules with little discussion available on their biological activities. With the purpose of bringing lights into this issue, we performed a revision of the literature and wrote this review based on some of the most current research reports of hydrazones and derivatives, making it clear that the synthesis of these molecules can lead to new drug prototypes. Our goal is to encourage more studies focused on the synthesis and evaluation of new hydrazones, as a contribution to the development of potential new drugs for the treatment of various diseases.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30107 - Medicinal chemistry

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Mini-reviews in medicinal chemistry

ISSN

1389-5575

e-ISSN

1875-5607

Svazek periodika

20

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

AE - Spojené arabské emiráty

Počet stran výsledku

27

Strana od-do

342-368

Kód UT WoS článku

000529800800001

EID výsledku v databázi Scopus

2-s2.0-85084273266