Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F65269705%3A_____%2F19%3A00070685" target="_blank" >RIV/65269705:_____/19:00070685 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216224:14110/19:00109783

Výsledek na webu

<a href="https://journals.lww.com/md-journal/fulltext/2019/04260/Do_lumbar_magnetic_resonance_imaging_changes.79.aspx" target="_blank" >https://journals.lww.com/md-journal/fulltext/2019/04260/Do_lumbar_magnetic_resonance_imaging_changes.79.aspx</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1097/MD.0000000000015377" target="_blank" >10.1097/MD.0000000000015377</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?

Popis výsledku v původním jazyce

The aim of this observational, cross-sectional study was to analyse lumbar magnetic resonance imaging (MRI) findings in patients with non-specific chronic low back pain (CLBP), and to evaluate any correlation with pain intensity and their capacity to predict neuropathic pain (NP) in these patients. Fifty-two patients with non-specific CLBP, between 21 and 62 years of age, 50% men, were investigated. Lumbar MRI was employed to assess disc degeneration, endplate changes, Modic changes, disc displacement, facet degeneration, foraminal stenosis and central lumbar spinal stenosis. The characteristics of pain were evaluated and patients were divided into 2 subgroups: with NP (24 patients) and without NP (28 patients), based on the results of a DN4-interview. Correlations between particular MRI changes and their relations to the intensity of pain were evaluated. Logistic regression was used to disclose predictors of NP. Lumbar spine degenerative features were frequent in patients with non-specific CLBP, with L4/5 the most affected level. A significant correlation emerged between the severity of degenerative changes in particular lumbar spine structures (correlation coefficient ranging between 0.325 and 0.573), while no correlation was found between severity of degenerative changes and pain. Multivariate logistic regression revealed only 2 independent predictors of NP -female sex (odds ratio [OR]=11.9) and a mean pain intensity of &gt;= 4.5 in the previous 4 weeks (OR=13.1). Degenerative changes in the lumbar spine are frequent MRI findings, but do not correlate with the intensity of pain and do not predict NP. However, female sex and pain intensity do predict NP.

Název v anglickém jazyce

Do lumbar magnetic resonance imaging changes predict neuropathic pain in patients with chronic non-specific low back pain?

Popis výsledku anglicky

The aim of this observational, cross-sectional study was to analyse lumbar magnetic resonance imaging (MRI) findings in patients with non-specific chronic low back pain (CLBP), and to evaluate any correlation with pain intensity and their capacity to predict neuropathic pain (NP) in these patients. Fifty-two patients with non-specific CLBP, between 21 and 62 years of age, 50% men, were investigated. Lumbar MRI was employed to assess disc degeneration, endplate changes, Modic changes, disc displacement, facet degeneration, foraminal stenosis and central lumbar spinal stenosis. The characteristics of pain were evaluated and patients were divided into 2 subgroups: with NP (24 patients) and without NP (28 patients), based on the results of a DN4-interview. Correlations between particular MRI changes and their relations to the intensity of pain were evaluated. Logistic regression was used to disclose predictors of NP. Lumbar spine degenerative features were frequent in patients with non-specific CLBP, with L4/5 the most affected level. A significant correlation emerged between the severity of degenerative changes in particular lumbar spine structures (correlation coefficient ranging between 0.325 and 0.573), while no correlation was found between severity of degenerative changes and pain. Multivariate logistic regression revealed only 2 independent predictors of NP -female sex (odds ratio [OR]=11.9) and a mean pain intensity of &gt;= 4.5 in the previous 4 weeks (OR=13.1). Degenerative changes in the lumbar spine are frequent MRI findings, but do not correlate with the intensity of pain and do not predict NP. However, female sex and pain intensity do predict NP.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30218 - General and internal medicine

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Medicine

ISSN

0025-7974

e-ISSN

—

Svazek periodika

98

Číslo periodika v rámci svazku

17

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

9

Strana od-do

"e15377"

Kód UT WoS článku

000467337400079

EID výsledku v databázi Scopus

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