Microdevices for Cell Stimulation: Integrated Zinc Oxide Piezoelectric Nanostructures in Silicon Microparticles

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F21%3A00549811" target="_blank" >RIV/67985823:_____/21:00549811 - isvavai.cz</a>

Výsledek na webu

<a href="https://ieeexplore.ieee.org/document/9375134" target="_blank" >https://ieeexplore.ieee.org/document/9375134</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/MEMS51782.2021.9375134" target="_blank" >10.1109/MEMS51782.2021.9375134</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Microdevices for Cell Stimulation: Integrated Zinc Oxide Piezoelectric Nanostructures in Silicon Microparticles

Popis výsledku v původním jazyce

Bioelectronic medicine is acquiring importance within the field of regenerative medicine. Several types of cells migrate, differentiate or proliferate in response to electrical stimuli, promoting tissue regeneration. Piezoelectric nanogenerators (NGs) are capable of electrically stimulate cells in a wireless way through acoustic power, broadening the scope of materials used for biomedical applications.In this work, microdevices consisting of piezoelectric zinc oxide nanosheets (ZnO NSs) integrated on silicon microparticles were synthesized. Finite element modelling (FEM) simulations demonstrate that these microdevices are able to produce electric fields (EF) in response to mechanical stresses or ultrasonic waves. In vitro testing with osteoblast Saos-2 cells proved their cytocompatibility. Soon, the use of these simple, costless and technologically reproducible microdevices may offer new ways to develop bioelectronic therapies.

Název v anglickém jazyce

Microdevices for Cell Stimulation: Integrated Zinc Oxide Piezoelectric Nanostructures in Silicon Microparticles

Popis výsledku anglicky

Bioelectronic medicine is acquiring importance within the field of regenerative medicine. Several types of cells migrate, differentiate or proliferate in response to electrical stimuli, promoting tissue regeneration. Piezoelectric nanogenerators (NGs) are capable of electrically stimulate cells in a wireless way through acoustic power, broadening the scope of materials used for biomedical applications.In this work, microdevices consisting of piezoelectric zinc oxide nanosheets (ZnO NSs) integrated on silicon microparticles were synthesized. Finite element modelling (FEM) simulations demonstrate that these microdevices are able to produce electric fields (EF) in response to mechanical stresses or ultrasonic waves. In vitro testing with osteoblast Saos-2 cells proved their cytocompatibility. Soon, the use of these simple, costless and technologically reproducible microdevices may offer new ways to develop bioelectronic therapies.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

30402 - Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)

Projekt

<a href="/cs/project/GA20-01570S" target="_blank" >GA20-01570S: Zlepšení osteointegrace kostních implantátů jejich pokrytím feroelektrickými vrstvami</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

34th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2021

ISBN

978-1-6654-1912-3

ISSN

—

e-ISSN

—

Počet stran výsledku

4

Strana od-do

559-562

Název nakladatele

IEEE

Místo vydání

New York

Místo konání akce

Gainesville

Datum konání akce

25. 1. 2021

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000667731600137