Experimental evaluation of mechanical and electrical properties of RBC suspensions under flow. Role of RBC deformability

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985874%3A_____%2F10%3A00347992" target="_blank" >RIV/67985874:_____/10:00347992 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Experimental evaluation of mechanical and electrical properties of RBC suspensions under flow. Role of RBC deformability

Popis výsledku v původním jazyce

Mechanical and electrical properties of altered RBC suspensions from whole normal human blood were evaluated through apparent viscosity and conductivity measurements under different flow conditions. RBC suspensions were made by mixing constant volume ofthe washed control and treated RBC in isotonic physiological solution, Dextran 70 and polyethileneglycol (PEG) of different concentrations. A decrease in RBC deformability was achieved by treatment with glutaraldehyde (0.01?1.0%). The samples were measured under different transient flow regimes at low shear rates and at different local structure of flow. The dependences of the conductivity and the apparent viscosity on time and shear rates were studied in parallel with the changes in concentrations of Dextran 70, PEG and glutaraldehyde. The results show that the apparent viscosity and conductivity of RBC suspensions in Dextran 70 and PEG are strongly influenced by flow, shear rates and concentration and deformability of cells.

Název v anglickém jazyce

Experimental evaluation of mechanical and electrical properties of RBC suspensions under flow. Role of RBC deformability

Popis výsledku anglicky

Mechanical and electrical properties of altered RBC suspensions from whole normal human blood were evaluated through apparent viscosity and conductivity measurements under different flow conditions. RBC suspensions were made by mixing constant volume ofthe washed control and treated RBC in isotonic physiological solution, Dextran 70 and polyethileneglycol (PEG) of different concentrations. A decrease in RBC deformability was achieved by treatment with glutaraldehyde (0.01?1.0%). The samples were measured under different transient flow regimes at low shear rates and at different local structure of flow. The dependences of the conductivity and the apparent viscosity on time and shear rates were studied in parallel with the changes in concentrations of Dextran 70, PEG and glutaraldehyde. The results show that the apparent viscosity and conductivity of RBC suspensions in Dextran 70 and PEG are strongly influenced by flow, shear rates and concentration and deformability of cells.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BK - Mechanika tekutin

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Series on biomechanics

ISSN

1313-2458

e-ISSN

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Svazek periodika

25

Číslo periodika v rámci svazku

3-4

Stát vydavatele periodika

BG - Bulharská republika

Počet stran výsledku

8

Strana od-do

45-52

Kód UT WoS článku

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EID výsledku v databázi Scopus

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