Study of rheological and electrical behaviour of RBC suspensions in dextran and PEG under non-steady flow. Role of RBC deformability and morphology

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985874%3A_____%2F10%3A00348106" target="_blank" >RIV/67985874:_____/10:00348106 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Study of rheological and electrical behaviour of RBC suspensions in dextran and PEG under non-steady flow. Role of RBC deformability and morphology

Popis výsledku v původním jazyce

The electrical conductivity and shear rate dependences in parallel with the rheological properties of the samples were studied under transient flow regimes at different local structure of the uniform Couette flow. Red blood cells (RBC) were treated withglutaraldehyde (GA) with different concentrations (from 0,01% to 1%). A time course of conductivity of normal RBC and treated with GA suspended in dextran 70 was recorded under trapezoid change of shear rates. It provides experimental description of RBCaggregation-disaggregation processes and other cell-cell interactions. Dextrans induce morphological alterations in RBC shape and arrangement in the suspensions. Echinocytes are observed at low Dx 70 concentrations while spherocytes are found mainly in smears at higher Dx 70 concentrations. Their morphological characteristics affect blood electrical and mechanical properties.

Název v anglickém jazyce

Study of rheological and electrical behaviour of RBC suspensions in dextran and PEG under non-steady flow. Role of RBC deformability and morphology

Popis výsledku anglicky

The electrical conductivity and shear rate dependences in parallel with the rheological properties of the samples were studied under transient flow regimes at different local structure of the uniform Couette flow. Red blood cells (RBC) were treated withglutaraldehyde (GA) with different concentrations (from 0,01% to 1%). A time course of conductivity of normal RBC and treated with GA suspended in dextran 70 was recorded under trapezoid change of shear rates. It provides experimental description of RBCaggregation-disaggregation processes and other cell-cell interactions. Dextrans induce morphological alterations in RBC shape and arrangement in the suspensions. Echinocytes are observed at low Dx 70 concentrations while spherocytes are found mainly in smears at higher Dx 70 concentrations. Their morphological characteristics affect blood electrical and mechanical properties.

Druh

D - Stať ve sborníku

CEP obor

BK - Mechanika tekutin

OECD FORD obor

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Projekt

<a href="/cs/project/IAA200600803" target="_blank" >IAA200600803: Vliv zpevnění nanočásticemi na mez toku a plastickou deformaci skelných polymerů a jejich teplotní konsolidaci</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

6th World Congress of Biomechanics (WCB 2010)

ISBN

978-3-642-14514-8

ISSN

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e-ISSN

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Počet stran výsledku

4

Strana od-do

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Název nakladatele

Springer

Místo vydání

Heidelberg

Místo konání akce

Singapore

Datum konání akce

1. 8. 2010

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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