Experimental evaluation of mechanical and electrical properties of RBC suspensions in Dextran and PEG under flow II. Role of RBC deformability and morphology

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985874%3A_____%2F11%3A00371729" target="_blank" >RIV/67985874:_____/11:00371729 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.3233/CH-2011-1494" target="_blank" >http://dx.doi.org/10.3233/CH-2011-1494</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3233/CH-2011-1494" target="_blank" >10.3233/CH-2011-1494</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Experimental evaluation of mechanical and electrical properties of RBC suspensions in Dextran and PEG under flow II. Role of RBC deformability and morphology

Popis výsledku v původním jazyce

Mechanical and electrical properties of the normal RBC suspensions and of hardened after treatment with glutaraldehyde RBCs in isotonic physiological solution, dextran 70 and polyethylene glycol (PEG) were evaluated. Apparent viscosity and conductivity were measured under steady and transient flow regimes at low shear rates and different local structure of the flow. A time course of conductivity was recorded in parallel with the rheological properties of the RBC suspensions. The conductivity and apparent viscosity dependences on shear rates were measured and compared at different concentrations of dextran 70, PEG and glutaraldehyde. Echinocytes are observed at low dextran 70 and PEG concentrations while spherocytes are found mainly in smears treated with higher concentrations. The results show that the apparent viscosity and conductivity of RBC suspensions in dextran 70 and PEG are strongly influenced by flow, shear rates, concentration, cell deformability and morphology.

Název v anglickém jazyce

Experimental evaluation of mechanical and electrical properties of RBC suspensions in Dextran and PEG under flow II. Role of RBC deformability and morphology

Popis výsledku anglicky

Mechanical and electrical properties of the normal RBC suspensions and of hardened after treatment with glutaraldehyde RBCs in isotonic physiological solution, dextran 70 and polyethylene glycol (PEG) were evaluated. Apparent viscosity and conductivity were measured under steady and transient flow regimes at low shear rates and different local structure of the flow. A time course of conductivity was recorded in parallel with the rheological properties of the RBC suspensions. The conductivity and apparent viscosity dependences on shear rates were measured and compared at different concentrations of dextran 70, PEG and glutaraldehyde. Echinocytes are observed at low dextran 70 and PEG concentrations while spherocytes are found mainly in smears treated with higher concentrations. The results show that the apparent viscosity and conductivity of RBC suspensions in dextran 70 and PEG are strongly influenced by flow, shear rates, concentration, cell deformability and morphology.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BK - Mechanika tekutin

OECD FORD obor

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Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2011

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Clinical Hemorheology and Microcirculation

ISSN

1386-0291

e-ISSN

—

Svazek periodika

49

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

10

Strana od-do

441-450

Kód UT WoS článku

000298858400044

EID výsledku v databázi Scopus

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