Advances in separation and identification of biologically importantmilk proteins and peptides
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F24%3A00572699" target="_blank" >RIV/68081715:_____/24:00572699 - isvavai.cz</a>
Výsledek na webu
<a href="https://hdl.handle.net/11104/0343306" target="_blank" >https://hdl.handle.net/11104/0343306</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elps.202300084" target="_blank" >10.1002/elps.202300084</a>
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Advances in separation and identification of biologically importantmilk proteins and peptides
Popis výsledku v původním jazyce
Milk is a rich source of biologically important proteins and peptides. In addition, milk contains a variety of extracellular vesicles (EVs), including exosomes, that carry their own proteome cargo. EVs are essential for cell-cell communication and modulation of biological processes. They act as nature carriers of bioactive proteins/peptides in targeted delivery during various physiological and pathological conditions. Identification of the proteins and protein-derived peptides in milk and EVs and recognition of their biological activities and functions had a tremendous impact on food industry, medicine research, and clinical applications. Advanced separation methods, mass spectrometry (MS)-based proteomic approaches and innovative biostatistical procedures allowed for characterization of milk protein isoforms, genetic/splice variants, posttranslational modifications and their key roles, and contributed to novel discoveries. This review article discusses recently published developments in separation and identification of bioactive proteins/peptides from milk and milk EVs, including MS-based proteomic approaches.
Název v anglickém jazyce
Advances in separation and identification of biologically importantmilk proteins and peptides
Popis výsledku anglicky
Milk is a rich source of biologically important proteins and peptides. In addition, milk contains a variety of extracellular vesicles (EVs), including exosomes, that carry their own proteome cargo. EVs are essential for cell-cell communication and modulation of biological processes. They act as nature carriers of bioactive proteins/peptides in targeted delivery during various physiological and pathological conditions. Identification of the proteins and protein-derived peptides in milk and EVs and recognition of their biological activities and functions had a tremendous impact on food industry, medicine research, and clinical applications. Advanced separation methods, mass spectrometry (MS)-based proteomic approaches and innovative biostatistical procedures allowed for characterization of milk protein isoforms, genetic/splice variants, posttranslational modifications and their key roles, and contributed to novel discoveries. This review article discusses recently published developments in separation and identification of bioactive proteins/peptides from milk and milk EVs, including MS-based proteomic approaches.
Klasifikace
Druh
J<sub>imp</sub> - Článek v periodiku v databázi Web of Science
CEP obor
—
OECD FORD obor
10406 - Analytical chemistry
Návaznosti výsledku
Projekt
<a href="/cs/project/GA23-04703S" target="_blank" >GA23-04703S: Alternativní příprava kapilárních monolitických kolon z diskrétních částic s využitím superkritické vody</a><br>
Návaznosti
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Ostatní
Rok uplatnění
2024
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Údaje specifické pro druh výsledku
Název periodika
Electrophoresis
ISSN
0173-0835
e-ISSN
1522-2683
Svazek periodika
45
Číslo periodika v rámci svazku
1-2
Stát vydavatele periodika
US - Spojené státy americké
Počet stran výsledku
19
Strana od-do
101-119
Kód UT WoS článku
001003011900001
EID výsledku v databázi Scopus
2-s2.0-85161593823