Rapid identification of pathogens in blood serum via Raman tweezers in combination with advanced processing methods

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F23%3A00579192" target="_blank" >RIV/68081731:_____/23:00579192 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00159816:_____/23:00079484 RIV/00216224:14110/23:00134679

Výsledek na webu

<a href="https://opg.optica.org/boe/fulltext.cfm?uri=boe-14-12-6410&id=542842" target="_blank" >https://opg.optica.org/boe/fulltext.cfm?uri=boe-14-12-6410&id=542842</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1364/BOE.503628" target="_blank" >10.1364/BOE.503628</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Rapid identification of pathogens in blood serum via Raman tweezers in combination with advanced processing methods

Popis výsledku v původním jazyce

Pathogenic microbes contribute to several major global diseases that kill millions of people every year. Bloodstream infections caused by these microbes are associated with high morbidity and mortality rates, which are among the most common causes of hospitalizations. The search for the “Holy Grail” in clinical diagnostic microbiology, a reliable, accurate, low cost, real-time, and easy-to-use diagnostic method, is one of the essential issues in clinical practice. These very critical conditions can be met by Raman tweezers in combination with advanced analysis methods. Here, we present a proof-of-concept study based on Raman tweezers combined with spectral mixture analysis that allows for the identification of microbial strains directly from human blood serum without user intervention, thus eliminating the influence of a data analyst.

Název v anglickém jazyce

Rapid identification of pathogens in blood serum via Raman tweezers in combination with advanced processing methods

Popis výsledku anglicky

Pathogenic microbes contribute to several major global diseases that kill millions of people every year. Bloodstream infections caused by these microbes are associated with high morbidity and mortality rates, which are among the most common causes of hospitalizations. The search for the “Holy Grail” in clinical diagnostic microbiology, a reliable, accurate, low cost, real-time, and easy-to-use diagnostic method, is one of the essential issues in clinical practice. These very critical conditions can be met by Raman tweezers in combination with advanced analysis methods. Here, we present a proof-of-concept study based on Raman tweezers combined with spectral mixture analysis that allows for the identification of microbial strains directly from human blood serum without user intervention, thus eliminating the influence of a data analyst.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10306 - Optics (including laser optics and quantum optics)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2023

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biomedical Optics Express

ISSN

2156-7085

e-ISSN

—

Svazek periodika

14

Číslo periodika v rámci svazku

12

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

12

Strana od-do

6410-6421

Kód UT WoS článku

001123729400003

EID výsledku v databázi Scopus

2-s2.0-85181986022