Injury of the brain and liver capillaries in lethal car accidents

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F17%3A00486611" target="_blank" >RIV/68378050:_____/17:00486611 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.4323/rjlm.2017.351" target="_blank" >http://dx.doi.org/10.4323/rjlm.2017.351</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4323/rjlm.2017.351" target="_blank" >10.4323/rjlm.2017.351</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Injury of the brain and liver capillaries in lethal car accidents

Popis výsledku v původním jazyce

The study is reporting about the range of changes in the brain and liver capillaries in lethal automobile collisions. We present five case studies, where there was no compression of the head and abdominal organs, but the cause of death was hypovolemic shock associated with excessive blood loss. During the autopsy we removed tissue samples which were subjected to standard processed in order to permit histological and immunohistochemical examinations. Slices of liver and brain tissue were immunostained for Bcl2L1, GFAP, IL-12, S100 and Vimentin. We found a wide range of changes in this material, with microbleeding, bloodstaining, relaxation of capillaries with release of erythrocytes into the periphery, as well as neuron, axon and supporting glial cells damage. We observed a relationship between the microruptures of brain capillaries and the death of adjacent astrocytes.

Název v anglickém jazyce

Injury of the brain and liver capillaries in lethal car accidents

Popis výsledku anglicky

The study is reporting about the range of changes in the brain and liver capillaries in lethal automobile collisions. We present five case studies, where there was no compression of the head and abdominal organs, but the cause of death was hypovolemic shock associated with excessive blood loss. During the autopsy we removed tissue samples which were subjected to standard processed in order to permit histological and immunohistochemical examinations. Slices of liver and brain tissue were immunostained for Bcl2L1, GFAP, IL-12, S100 and Vimentin. We found a wide range of changes in this material, with microbleeding, bloodstaining, relaxation of capillaries with release of erythrocytes into the periphery, as well as neuron, axon and supporting glial cells damage. We observed a relationship between the microruptures of brain capillaries and the death of adjacent astrocytes.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30109 - Pathology

Projekt

<a href="/cs/project/LQ1604" target="_blank" >LQ1604: BIOCEV - od základního k aplikovanému výzkumu</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Revista de Medicina Legala

ISSN

1221-8618

e-ISSN

—

Svazek periodika

25

Číslo periodika v rámci svazku

4

Stát vydavatele periodika

RO - Rumunsko

Počet stran výsledku

8

Strana od-do

351-358

Kód UT WoS článku

000422835900006

EID výsledku v databázi Scopus

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