Nanocarbon allotropes — graphene and nanocrystalline diamond — promote cell proliferation

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F16%3A00464157" target="_blank" >RIV/68378271:_____/16:00464157 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/61388955:_____/16:00464157 RIV/00216208:11310/16:10323870 RIV/68407700:21230/16:00302536 RIV/00216208:11110/16:10323870 RIV/00216208:11140/16:10323870

Výsledek na webu

<a href="http://dx.doi.org/10.1002/smll.201503749" target="_blank" >http://dx.doi.org/10.1002/smll.201503749</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/smll.201503749" target="_blank" >10.1002/smll.201503749</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Nanocarbon allotropes — graphene and nanocrystalline diamond — promote cell proliferation

Popis výsledku v původním jazyce

Two profoundly different carbon allotropes – nanocrystalline diamond and graphene – are of considerable interest from the viewpoint of a wide range of biomedical applications including implant coating, drug and gene delivery, cancer therapy, and biosensing. Osteoblast adhesion and proliferation on nanocrystalline diamond and graphene are compared under various conditions such as differences in wettability, topography, and the presence or absence of protein interlayers between cells and the substrate. The materials are characterized in detail by means of scanning electron microscopy, atomic force microscopy, photoelectron spectroscopy, Raman spectroscopy, and contact angle measurements. In vitro experiments have revealed a significantly higher degree of cell proliferation on graphene than on nanocrystalline diamond and a tissue culture polystyrene control material. Proliferation is promoted, in particular, by hydrophobic graphene with a large number of nanoscale wrinkles.n

Název v anglickém jazyce

Nanocarbon allotropes — graphene and nanocrystalline diamond — promote cell proliferation

Popis výsledku anglicky

Two profoundly different carbon allotropes – nanocrystalline diamond and graphene – are of considerable interest from the viewpoint of a wide range of biomedical applications including implant coating, drug and gene delivery, cancer therapy, and biosensing. Osteoblast adhesion and proliferation on nanocrystalline diamond and graphene are compared under various conditions such as differences in wettability, topography, and the presence or absence of protein interlayers between cells and the substrate. The materials are characterized in detail by means of scanning electron microscopy, atomic force microscopy, photoelectron spectroscopy, Raman spectroscopy, and contact angle measurements. In vitro experiments have revealed a significantly higher degree of cell proliferation on graphene than on nanocrystalline diamond and a tissue culture polystyrene control material. Proliferation is promoted, in particular, by hydrophobic graphene with a large number of nanoscale wrinkles.n

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Small

ISSN

1613-6810

e-ISSN

—

Svazek periodika

12

Číslo periodika v rámci svazku

18

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

11

Strana od-do

2499-2509

Kód UT WoS článku

000376611800013

EID výsledku v databázi Scopus

2-s2.0-84978324252