Molecular detection by liquid gated Hall effect measurements of graphene

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378271%3A_____%2F18%3A00501420" target="_blank" >RIV/68378271:_____/18:00501420 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1039/c7nr06330j" target="_blank" >http://dx.doi.org/10.1039/c7nr06330j</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1039/c7nr06330j" target="_blank" >10.1039/c7nr06330j</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Molecular detection by liquid gated Hall effect measurements of graphene

Popis výsledku v původním jazyce

Conventional electrical biosensing techniques include Cyclic Voltammetry (CV, amperometric) and ion-sensitive field effect transistors (ISFETs, potentiometric). However, CV is not able to detect electrochemically inactive molecules where there is no redox reaction in solution, and the resistance change in pristine ISFETs in response to low concentration solutions is not observable. Here, we show a very sensitive label-free biosensing method using Hall effect measurements on unfunctionalized graphene devices where the gate electrode is immersed in the solution containing the analyte of interest. This liquid gated Hall effect measurement (LGHM) technique is independent of redox reactions, and it enables the extraction of additional information regarding electrical properties from graphene as compared with ISFETs, which can be used to improve the sensitivity. We demonstrate that LGHM has a higher sensitivity than conventional biosensing methods for L-histidine in the pM range.n

Název v anglickém jazyce

Molecular detection by liquid gated Hall effect measurements of graphene

Popis výsledku anglicky

Conventional electrical biosensing techniques include Cyclic Voltammetry (CV, amperometric) and ion-sensitive field effect transistors (ISFETs, potentiometric). However, CV is not able to detect electrochemically inactive molecules where there is no redox reaction in solution, and the resistance change in pristine ISFETs in response to low concentration solutions is not observable. Here, we show a very sensitive label-free biosensing method using Hall effect measurements on unfunctionalized graphene devices where the gate electrode is immersed in the solution containing the analyte of interest. This liquid gated Hall effect measurement (LGHM) technique is independent of redox reactions, and it enables the extraction of additional information regarding electrical properties from graphene as compared with ISFETs, which can be used to improve the sensitivity. We demonstrate that LGHM has a higher sensitivity than conventional biosensing methods for L-histidine in the pM range.n

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10302 - Condensed matter physics (including formerly solid state physics, supercond.)

Projekt

—

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Nanoscale

ISSN

2040-3364

e-ISSN

—

Svazek periodika

10

Číslo periodika v rámci svazku

3

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

6

Strana od-do

930-935

Kód UT WoS článku

000423259000005

EID výsledku v databázi Scopus

2-s2.0-85040927118