Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378297%3A_____%2F14%3A00430530" target="_blank" >RIV/68378297:_____/14:00430530 - isvavai.cz</a>

Výsledek na webu

<a href="http://www.tandfonline.com/doi/abs/10.1080/10255842.2014.931078#.VBq66E0cRaQ" target="_blank" >http://www.tandfonline.com/doi/abs/10.1080/10255842.2014.931078#.VBq66E0cRaQ</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/10255842.2014.931078" target="_blank" >10.1080/10255842.2014.931078</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella

Popis výsledku v původním jazyce

Knowledge of the anisotropic elastic properties of osteon and osteonal lamellae is the key to a description of the elasticity of cortical bone. Various analytical and computational models have been proposed for predicting the mechanical properties of bone at different structural levels. (Hamed et al. 2010) modelled the hierarchical structure of bone at more than one level, using multiple step-by-step micromechanics-based homogenization to capture the behaviour of bone spanning from nano- to sub- microstructure levels. A feature of our model is that we have developed an inverse homogenization scheme from the macroscopic scale of cortical bone to the single lamella level. There are also experimental methods for studies of cortical bone at the level of osteon and osteonal lamella, e.g. instrumented nanoindentation (Lukes et al. 2009), atomic force microscopy (Lefevre et al. 2013) and the ultrasound method (Rho 1996). To validate the mathematical model presented here, we determined the mec

Název v anglickém jazyce

Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella

Popis výsledku anglicky

Knowledge of the anisotropic elastic properties of osteon and osteonal lamellae is the key to a description of the elasticity of cortical bone. Various analytical and computational models have been proposed for predicting the mechanical properties of bone at different structural levels. (Hamed et al. 2010) modelled the hierarchical structure of bone at more than one level, using multiple step-by-step micromechanics-based homogenization to capture the behaviour of bone spanning from nano- to sub- microstructure levels. A feature of our model is that we have developed an inverse homogenization scheme from the macroscopic scale of cortical bone to the single lamella level. There are also experimental methods for studies of cortical bone at the level of osteon and osteonal lamella, e.g. instrumented nanoindentation (Lukes et al. 2009), atomic force microscopy (Lefevre et al. 2013) and the ultrasound method (Rho 1996). To validate the mathematical model presented here, we determined the mec

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

JJ - Ostatní materiály

OECD FORD obor

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Projekt

<a href="/cs/project/GAP105%2F10%2F2305" target="_blank" >GAP105/10/2305: Morfometrické a mechanické vlastnosti trabekulární kosti zjištěné pomocí metod mikromechaniky a numerického modelování</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Computer methods in biomechanics and biomedical engineering

ISSN

1025-5842

e-ISSN

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Svazek periodika

17

Číslo periodika v rámci svazku

SUPP. 1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

2

Strana od-do

24-25

Kód UT WoS článku

000340376700013

EID výsledku v databázi Scopus

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