Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F14%3A00217611" target="_blank" >RIV/68407700:21220/14:00217611 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1080/10255842.2014.931078" target="_blank" >http://dx.doi.org/10.1080/10255842.2014.931078</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/10255842.2014.931078" target="_blank" >10.1080/10255842.2014.931078</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella

Popis výsledku v původním jazyce

Knowledge of the anisotropic elastic properties of osteon and osteonal lamellae is the key to a description of the elasticity of cortical bone. Various analytical and computational models have been proposed for predicting the mechanical properties of bone at different structural levels. (Hamed et al. 2010) modelled the hierarchical structure of bone at more than one level, using multiple step-by-step micromechanics-based homogenization to capture the behaviour of bone spanning from nano- to sub- microstructure levels. A feature of our model is that we have developed an inverse homogenization scheme from the macroscopic scale of cortical bone to the single lamella level. There are also experimental methods for studies of cortical bone at the level of osteon and osteonal lamella, e.g. instrumented nanoindentation (Lukes et al. 2009), atomic force microscopy (Lefevre et al. 2013) and the ultrasound method (Rho 1996). To validate the mathematical model presented here, we determined the mechanical properties of a single lamella in three perpendicular directions using instrumented nanoindentation.

Název v anglickém jazyce

Mathematical model of human osteon and its validation by nanomechanical testing of bone lamella

Popis výsledku anglicky

Knowledge of the anisotropic elastic properties of osteon and osteonal lamellae is the key to a description of the elasticity of cortical bone. Various analytical and computational models have been proposed for predicting the mechanical properties of bone at different structural levels. (Hamed et al. 2010) modelled the hierarchical structure of bone at more than one level, using multiple step-by-step micromechanics-based homogenization to capture the behaviour of bone spanning from nano- to sub- microstructure levels. A feature of our model is that we have developed an inverse homogenization scheme from the macroscopic scale of cortical bone to the single lamella level. There are also experimental methods for studies of cortical bone at the level of osteon and osteonal lamella, e.g. instrumented nanoindentation (Lukes et al. 2009), atomic force microscopy (Lefevre et al. 2013) and the ultrasound method (Rho 1996). To validate the mathematical model presented here, we determined the mechanical properties of a single lamella in three perpendicular directions using instrumented nanoindentation.

Druh

D - Stať ve sborníku

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

<a href="/cs/project/TA01010185" target="_blank" >TA01010185: Nové materiály a povrchové vrstvy pro bionický návrh kloubních náhrad</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Computer Methods in Biomechanics and Biomedical Engineering

ISBN

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ISSN

1025-5842

e-ISSN

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Počet stran výsledku

2

Strana od-do

24-25

Název nakladatele

Taylor & Francis

Místo vydání

London

Místo konání akce

Valenciennes

Datum konání akce

27. 8. 2014

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

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