NANOINDENTATION OF 3D PRINTED POLYLACTIC ACID BONE SCAFFOLD

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F15%3A00301025" target="_blank" >RIV/68407700:21220/15:00301025 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21260/15:00301025

Výsledek na webu

<a href="http://www.czech-in.org/ESB/ESB2015_Abstract_Book.pdf" target="_blank" >http://www.czech-in.org/ESB/ESB2015_Abstract_Book.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

NANOINDENTATION OF 3D PRINTED POLYLACTIC ACID BONE SCAFFOLD

Popis výsledku v původním jazyce

Artificial bone scaffolds represent an attractive alternative to autografts and allografts used in orthopedic repairs of bone defects. Bone and bone microstructure adapted stiffness properties to their load bearing function; hence effective elastic properties of proposed bone scaffold should be similar enough to provide bone’s primary function of human body support. As an alternative to widely used bone autografts and allografts, artificial bone scaffolds have to exhibit similar bone integration properties in terms of tissue ingrowth, to allow nutrients to pass through the bone marrow and also to preserve high rates of bone regeneration. 3D printing of polylactic acid (PLA) can be successfully used for production of porous 3D structure that mimics bone tissue. However, final scaffold needs to be inspected for potential impurities and mechanical gradients due to hot rapid manufacturing process. Nanoindentation can effectively serve as a quality control tool at microscale.

Název v anglickém jazyce

NANOINDENTATION OF 3D PRINTED POLYLACTIC ACID BONE SCAFFOLD

Popis výsledku anglicky

Artificial bone scaffolds represent an attractive alternative to autografts and allografts used in orthopedic repairs of bone defects. Bone and bone microstructure adapted stiffness properties to their load bearing function; hence effective elastic properties of proposed bone scaffold should be similar enough to provide bone’s primary function of human body support. As an alternative to widely used bone autografts and allografts, artificial bone scaffolds have to exhibit similar bone integration properties in terms of tissue ingrowth, to allow nutrients to pass through the bone marrow and also to preserve high rates of bone regeneration. 3D printing of polylactic acid (PLA) can be successfully used for production of porous 3D structure that mimics bone tissue. However, final scaffold needs to be inspected for potential impurities and mechanical gradients due to hot rapid manufacturing process. Nanoindentation can effectively serve as a quality control tool at microscale.

Druh

O - Ostatní výsledky

CEP obor

BO - Biofyzika

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů