Correlation between adhesion strength and phase behaviour in solid-supported lipid membranes

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F20%3A00348915" target="_blank" >RIV/68407700:21220/20:00348915 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.1016/j.molliq.2020.114492" target="_blank" >https://doi.org/10.1016/j.molliq.2020.114492</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.molliq.2020.114492" target="_blank" >10.1016/j.molliq.2020.114492</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Correlation between adhesion strength and phase behaviour in solid-supported lipid membranes

Popis výsledku v původním jazyce

Fundamental understanding of vesicle adhesion in the size range <= 200 nm is of major importance when addressing biologically relevant processes involving the presence of small vesicles like exosomes or endosomes. Using quartz crystal microbalance with dissipation monitoring, we investigate the correlation between vesicle deformation and eventual membrane rupture on surfaces with different adhesion levels, as well as their respective thermotropic phase transitions. In particular, phase transitions of solid-supported membranes on Au resemble the cooperative behaviour of lipid membrane transitions in bulk. In contrast, solid-supported membranes on SiO2 exhibit broadened 'double-peak' transitions, rendering a 'decoupling' effect during melting due to stronger interactions with SiO2. This paper provides a comprehensive view of the correlation between size, geometry and phase transitions observed in the layer of adsorbed lipid vesicles/membranes. It paves the way to explore structural changes on more complex biointerfaces by acoustic-based sensors. (C) 2020 The Authors. Published by Elsevier B.V.

Název v anglickém jazyce

Correlation between adhesion strength and phase behaviour in solid-supported lipid membranes

Popis výsledku anglicky

Fundamental understanding of vesicle adhesion in the size range <= 200 nm is of major importance when addressing biologically relevant processes involving the presence of small vesicles like exosomes or endosomes. Using quartz crystal microbalance with dissipation monitoring, we investigate the correlation between vesicle deformation and eventual membrane rupture on surfaces with different adhesion levels, as well as their respective thermotropic phase transitions. In particular, phase transitions of solid-supported membranes on Au resemble the cooperative behaviour of lipid membrane transitions in bulk. In contrast, solid-supported membranes on SiO2 exhibit broadened 'double-peak' transitions, rendering a 'decoupling' effect during melting due to stronger interactions with SiO2. This paper provides a comprehensive view of the correlation between size, geometry and phase transitions observed in the layer of adsorbed lipid vesicles/membranes. It paves the way to explore structural changes on more complex biointerfaces by acoustic-based sensors. (C) 2020 The Authors. Published by Elsevier B.V.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

10300 - Physical sciences

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Molecular Liquids

ISSN

0167-7322

e-ISSN

1873-3166

Svazek periodika

320

Číslo periodika v rámci svazku

114492

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

11

Strana od-do

—

Kód UT WoS článku

000599310700040

EID výsledku v databázi Scopus

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