Advances in Biomembranes and Lipid Self-Assembly

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F21%3A00354276" target="_blank" >RIV/68407700:21220/21:00354276 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Advances in Biomembranes and Lipid Self-Assembly

Popis výsledku v původním jazyce

Lipid phase behavior in model membranes has been the subject of intensive research aiming to unravel fundamental mechanisms behind membrane function. Among the experimental techniques used for characterizing lipid phase transitions at different scale levels, quartz crystal microbalance with dissipation monitoring (QCM-D) has emerged as a useful approach for detecting phase transitions in solid-supported lipid membranes at the nano-mesoscale. In this chapter, we provide examples of how phase transitions in supported lipid membranes, detected by QCM-D, can be used as descriptors for monitoring specific lipid-membrane related mechanisms such as vesicle adsorption, changes in lipid organization upon addition of inclusions of small molecules and lipid transfer kinetics by monomer diffusion. Combined with other complementary techniques at a multiscale, QCM-D stands as a promising approach to be employed in monitoring the phase behavior of supported lipid membranes in particular and biomolecules in general.

Název v anglickém jazyce

Advances in Biomembranes and Lipid Self-Assembly

Popis výsledku anglicky

Lipid phase behavior in model membranes has been the subject of intensive research aiming to unravel fundamental mechanisms behind membrane function. Among the experimental techniques used for characterizing lipid phase transitions at different scale levels, quartz crystal microbalance with dissipation monitoring (QCM-D) has emerged as a useful approach for detecting phase transitions in solid-supported lipid membranes at the nano-mesoscale. In this chapter, we provide examples of how phase transitions in supported lipid membranes, detected by QCM-D, can be used as descriptors for monitoring specific lipid-membrane related mechanisms such as vesicle adsorption, changes in lipid organization upon addition of inclusions of small molecules and lipid transfer kinetics by monomer diffusion. Combined with other complementary techniques at a multiscale, QCM-D stands as a promising approach to be employed in monitoring the phase behavior of supported lipid membranes in particular and biomolecules in general.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

10301 - Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

Projekt

<a href="/cs/project/EF16_027%2F0008465" target="_blank" >EF16_027/0008465: Mezinárodní mobility výzkumných pracovníků ČVUT</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2021

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů