Dynamical profile of connectivity changes of ictal epileptic networks
Identifikátory výsledku
Kód výsledku v IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21230%2F15%3A00233145" target="_blank" >RIV/68407700:21230/15:00233145 - isvavai.cz</a>
Výsledek na webu
<a href="http://emps.exeter.ac.uk/media/universityofexeter/emps/research/dynamicsdays/ddays_exeter_abstracts_2015c.pdf" target="_blank" >http://emps.exeter.ac.uk/media/universityofexeter/emps/research/dynamicsdays/ddays_exeter_abstracts_2015c.pdf</a>
DOI - Digital Object Identifier
—
Alternativní jazyky
Jazyk výsledku
angličtina
Název v původním jazyce
Dynamical profile of connectivity changes of ictal epileptic networks
Popis výsledku v původním jazyce
How seizures emerge from the abnormal dynamics of epileptic networks is still not clear. To elucidate the mechanisms of seizure initiation and progression it is necessary to understand the complex interaction between the individual network components andto identify the critical ones. Recent studies have demonstrated dynamical reconfiguration of functional network connectivity at the onset of the seizure, particularly within the seizure onset area. In this study we have explored the functional connectivity changes in invasive recordings from candidates of epilepsy surgery who were implanted with intracranial electrodes. For the purpose of this study we have developed a novel method based on multivariate directed transfer function (DTF) estimation, which is characterized by higher temporal resolution and improved statistical reliability when compared to traditional DTF techniques. Application to intracranial data enabled determination of the a priori probability of seizure connectivity
Název v anglickém jazyce
Dynamical profile of connectivity changes of ictal epileptic networks
Popis výsledku anglicky
How seizures emerge from the abnormal dynamics of epileptic networks is still not clear. To elucidate the mechanisms of seizure initiation and progression it is necessary to understand the complex interaction between the individual network components andto identify the critical ones. Recent studies have demonstrated dynamical reconfiguration of functional network connectivity at the onset of the seizure, particularly within the seizure onset area. In this study we have explored the functional connectivity changes in invasive recordings from candidates of epilepsy surgery who were implanted with intracranial electrodes. For the purpose of this study we have developed a novel method based on multivariate directed transfer function (DTF) estimation, which is characterized by higher temporal resolution and improved statistical reliability when compared to traditional DTF techniques. Application to intracranial data enabled determination of the a priori probability of seizure connectivity
Klasifikace
Druh
O - Ostatní výsledky
CEP obor
JA - Elektronika a optoelektronika, elektrotechnika
OECD FORD obor
—
Návaznosti výsledku
Projekt
Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.
Návaznosti
S - Specificky vyzkum na vysokych skolach
Ostatní
Rok uplatnění
2015
Kód důvěrnosti údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů