Animal 3D brain-mapping

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F16%3A00304834" target="_blank" >RIV/68407700:21460/16:00304834 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Animal 3D brain-mapping

Popis výsledku v původním jazyce

Introduction To this date there are no standardized mapping methods that display animal cortical EEG on the brain surface. Therefore, this study describes a 3D imaging method to be used for EEG mapping on the surface of the rat brain. The aim of our study was to develop a software module and a standard for statistical brain mapping. Animal EEG data recorded during behavioral activity and inactivity served as a subject for analysis and brain mapping. Methods In this study we measured electrical activity of the rat brain. For imaging purpose, we used 3D brain model from atlas [1] and adjusted it for our own module. We confirmed the validity of the 3D brain model by comparing the dimensions of normalized brain scans of 9 rats of the Wistar strain typically used in our laboratories. We have created a MATLAB module for brain mapping with the use of the rat brain model and a possibility to place any number of electrodes on the surface of the rat brain. The spline interpolation was used for imaging activity on surface of the brain [2] and statistical brain-mapping was used to compare the two example behavioral conditions. Results The module was effectively used to display EEG activity on the 3D surface and to display the statistical group differences in the sample of the animal data between behavioral activity and inactivity. The module can also compare data from individual measurement with a group mean. Conclusions This study describes computation of splines interpolation curves that are important for the brain mapping in rats. This approach will be used for effective comparisons of brain activity of rats under various conditions and with variable number and placement of cortical electrodes.

Název v anglickém jazyce

Animal 3D brain-mapping

Popis výsledku anglicky

Introduction To this date there are no standardized mapping methods that display animal cortical EEG on the brain surface. Therefore, this study describes a 3D imaging method to be used for EEG mapping on the surface of the rat brain. The aim of our study was to develop a software module and a standard for statistical brain mapping. Animal EEG data recorded during behavioral activity and inactivity served as a subject for analysis and brain mapping. Methods In this study we measured electrical activity of the rat brain. For imaging purpose, we used 3D brain model from atlas [1] and adjusted it for our own module. We confirmed the validity of the 3D brain model by comparing the dimensions of normalized brain scans of 9 rats of the Wistar strain typically used in our laboratories. We have created a MATLAB module for brain mapping with the use of the rat brain model and a possibility to place any number of electrodes on the surface of the rat brain. The spline interpolation was used for imaging activity on surface of the brain [2] and statistical brain-mapping was used to compare the two example behavioral conditions. Results The module was effectively used to display EEG activity on the 3D surface and to display the statistical group differences in the sample of the animal data between behavioral activity and inactivity. The module can also compare data from individual measurement with a group mean. Conclusions This study describes computation of splines interpolation curves that are important for the brain mapping in rats. This approach will be used for effective comparisons of brain activity of rats under various conditions and with variable number and placement of cortical electrodes.

Druh

O - Ostatní výsledky

CEP obor

IN - Informatika

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2016

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů