Simple Design of Mechanical Ventilator for Mass Production May Offer Excellent Performance, Precise Monitoring, and Advanced Safety

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F25%3A00383675" target="_blank" >RIV/68407700:21460/25:00383675 - isvavai.cz</a>

Výsledek na webu

<a href="https://doi.org/10.3390/app15105631" target="_blank" >https://doi.org/10.3390/app15105631</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/app15105631" target="_blank" >10.3390/app15105631</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Simple Design of Mechanical Ventilator for Mass Production May Offer Excellent Performance, Precise Monitoring, and Advanced Safety

Popis výsledku v původním jazyce

The COVID-19 pandemic raised global concerns about the shortage of ventilators and revealed the challenges of rapidly scaling up production to meet emergency needs. In response, numerous teams worldwide attempted to develop emergency and simple mechanical ventilators. Among these, the CoroVent ventilator was developed to meet the urgent need for ventilatory support in the Czech Republic. The aim of this study was to describe the innovative and simple design of the CoroVent emergency ventilator, evaluate its compliance with international safety and performance standards, verify its reliability under simulated clinical conditions, and demonstrate its suitability for use in crisis scenarios. CoroVent was designed with a focus on the clinical needs of patients with COVID-19 respiratory failure and to ensure safe ventilation while maintaining a simplified design. It features volume-controlled, pressure-limited mandatory ventilation and supports key adjustable parameters such as tidal volume, respiratory rate, inspiratory-to-expiratory time ratio, inspired oxygen fraction, and positive end-expiratory pressure (PEEP). The ventilator incorporates robust safety mechanisms, including alarms and a safety relief valve, to protect against excessive airway pressures. Results confirmed the ability to maintain consistent tidal volumes, stable PEEP, and precise pressure limitation over extended periods of use. The results showed that CoroVent met the essential international standards for accuracy, including those set by the UK Medicines and Healthcare products Regulatory Agency, U.S. Food and Drug Administration, and ISO 80601-2-12. Although production of these ventilators was stopped in 2021 as the Czech Republic managed the crisis and shortage of ventilators, the results validate their reliability as emergency ventilators and indicate their potential to support critical care needs in crisis situations.

Název v anglickém jazyce

Simple Design of Mechanical Ventilator for Mass Production May Offer Excellent Performance, Precise Monitoring, and Advanced Safety

Popis výsledku anglicky

The COVID-19 pandemic raised global concerns about the shortage of ventilators and revealed the challenges of rapidly scaling up production to meet emergency needs. In response, numerous teams worldwide attempted to develop emergency and simple mechanical ventilators. Among these, the CoroVent ventilator was developed to meet the urgent need for ventilatory support in the Czech Republic. The aim of this study was to describe the innovative and simple design of the CoroVent emergency ventilator, evaluate its compliance with international safety and performance standards, verify its reliability under simulated clinical conditions, and demonstrate its suitability for use in crisis scenarios. CoroVent was designed with a focus on the clinical needs of patients with COVID-19 respiratory failure and to ensure safe ventilation while maintaining a simplified design. It features volume-controlled, pressure-limited mandatory ventilation and supports key adjustable parameters such as tidal volume, respiratory rate, inspiratory-to-expiratory time ratio, inspired oxygen fraction, and positive end-expiratory pressure (PEEP). The ventilator incorporates robust safety mechanisms, including alarms and a safety relief valve, to protect against excessive airway pressures. Results confirmed the ability to maintain consistent tidal volumes, stable PEEP, and precise pressure limitation over extended periods of use. The results showed that CoroVent met the essential international standards for accuracy, including those set by the UK Medicines and Healthcare products Regulatory Agency, U.S. Food and Drug Administration, and ISO 80601-2-12. Although production of these ventilators was stopped in 2021 as the Czech Republic managed the crisis and shortage of ventilators, the results validate their reliability as emergency ventilators and indicate their potential to support critical care needs in crisis situations.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

20601 - Medical engineering

Projekt

—

Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2025

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Applied Sciences

ISSN

2076-3417

e-ISSN

2076-3417

Svazek periodika

15

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

CH - Švýcarská konfederace

Počet stran výsledku

16

Strana od-do

1-16

Kód UT WoS článku

001495780400001

EID výsledku v databázi Scopus

2-s2.0-105006749316