BrachyView: Combining LDR seed positions with transrectal ultrasound imaging in a prostate gel phantom

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21670%2F17%3A00329986" target="_blank" >RIV/68407700:21670/17:00329986 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.ejmp.2017.01.012" target="_blank" >http://dx.doi.org/10.1016/j.ejmp.2017.01.012</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ejmp.2017.01.012" target="_blank" >10.1016/j.ejmp.2017.01.012</a>

Jazyk výsledku

angličtina

Název v původním jazyce

BrachyView: Combining LDR seed positions with transrectal ultrasound imaging in a prostate gel phantom

Popis výsledku v původním jazyce

Purpose: BrachyView is a novel in-body imaging system which aims to provide LDR brachytherapy seeds position reconstruction within the prostate in real-time. The first prototype is presented in this study: the probe consists of a gamma camera featuring three single cone pinhole collimators embedded in a tungsten tube, above three, high resolution pixelated detectors (Timepix). Methods: The prostate was imaged with a TRUS system using a sagittal crystal with a 2.5 mm slice thickness. Eleven needles containing a total of thirty 0.508 (UI)-I-125 seeds were implanted under ultrasound guidance. A CT scan was used to localise the seed positions, as well as provide a reference when performing the image co-registration between the BrachyView coordinate system and the TRUS coordinate system. An in-house visualisation software interface was developed to provide a quantitative 3D reconstructed prostate based on the TRUS images and co-registered with the LDR seeds in situ. A rigid body image registration was performed between the BrachyView and TRUS systems, with the BrachyView and CT-derived source locations compared. Results: The reconstructed seed positions determined by the BrachyView probe showed a maximum discrepancy of 1.78 mm, with 75% of the seeds reconstructed within 1 mm of their nominal location. An accurate co-registration between the BrachyView and TRUS coordinate system was established. Conclusions: The BrachyView system has shown its ability to reconstruct all implanted LDR seeds within a tissue equivalent prostate gel phantom, providing both anatomical and seed position information in a single interface.

Název v anglickém jazyce

BrachyView: Combining LDR seed positions with transrectal ultrasound imaging in a prostate gel phantom

Popis výsledku anglicky

Purpose: BrachyView is a novel in-body imaging system which aims to provide LDR brachytherapy seeds position reconstruction within the prostate in real-time. The first prototype is presented in this study: the probe consists of a gamma camera featuring three single cone pinhole collimators embedded in a tungsten tube, above three, high resolution pixelated detectors (Timepix). Methods: The prostate was imaged with a TRUS system using a sagittal crystal with a 2.5 mm slice thickness. Eleven needles containing a total of thirty 0.508 (UI)-I-125 seeds were implanted under ultrasound guidance. A CT scan was used to localise the seed positions, as well as provide a reference when performing the image co-registration between the BrachyView coordinate system and the TRUS coordinate system. An in-house visualisation software interface was developed to provide a quantitative 3D reconstructed prostate based on the TRUS images and co-registered with the LDR seeds in situ. A rigid body image registration was performed between the BrachyView and TRUS systems, with the BrachyView and CT-derived source locations compared. Results: The reconstructed seed positions determined by the BrachyView probe showed a maximum discrepancy of 1.78 mm, with 75% of the seeds reconstructed within 1 mm of their nominal location. An accurate co-registration between the BrachyView and TRUS coordinate system was established. Conclusions: The BrachyView system has shown its ability to reconstruct all implanted LDR seeds within a tissue equivalent prostate gel phantom, providing both anatomical and seed position information in a single interface.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

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OECD FORD obor

30224 - Radiology, nuclear medicine and medical imaging

Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

PHYSICA MEDICA-EUROPEAN JOURNAL OF MEDICAL PHYSICS

ISSN

1120-1797

e-ISSN

1724-191X

Svazek periodika

34

Číslo periodika v rámci svazku

February

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

10

Strana od-do

55-64

Kód UT WoS článku

000395371000007

EID výsledku v databázi Scopus

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