Responses of midbrain auditory neurons to two different environmental sounds – a new approach on cross-sound modeling

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21730%2F20%3A00332494" target="_blank" >RIV/68407700:21730/20:00332494 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378041:_____/20:00539954

Výsledek na webu

<a href="https://www.sciencedirect.com/science/article/pii/S0303264719300851" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0303264719300851</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.biosystems.2019.104021" target="_blank" >10.1016/j.biosystems.2019.104021</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Responses of midbrain auditory neurons to two different environmental sounds – a new approach on cross-sound modeling

Popis výsledku v původním jazyce

When modeling auditory responses to environmental sounds, results are satisfactory if both training and testing are restricted to datasets of one type of sound. To predict 'cross-sound' responses (i.e., to predict the response to one type of sound e.g., rat Eating sound, after training with another type of sound e.g., rat Drinking sound), performance is typically poor. Here we implemented a novel approach to improve such cross-sound modeling (single unit datasets were collected at the auditory midbrain of anesthetized rats). The method had two key features: (a) population responses (e.g., average of 32 units) instead of responses of individual units were analyzed; and (b) the long sound segment was first divided into short segments (single sound-bouts), their similarity was then computed over a new metric involving the response (called Stimulus Response Model map or SRM map), and finally similar sound-bouts (regardless of sound type) and their associated responses (peri-stimulus time histograms, PSTHs) were modelled. Specifically, a committee machine model (artificial neural networks with 20 stratified spectral inputs) was trained with datasets from one sound type before predicting PSTH responses to another sound type. Model performance was markedly improved by up to 92%. Results also suggested the involvement of different neural mechanisms in generating the early and late responses to amplitude transients in the broadband environmental sounds. We concluded that it is possible to perform rather satisfactory cross-sound modeling on datasets grouped together based on their similarities in terms of the new metric of SRM map.

Název v anglickém jazyce

Responses of midbrain auditory neurons to two different environmental sounds – a new approach on cross-sound modeling

Popis výsledku anglicky

When modeling auditory responses to environmental sounds, results are satisfactory if both training and testing are restricted to datasets of one type of sound. To predict 'cross-sound' responses (i.e., to predict the response to one type of sound e.g., rat Eating sound, after training with another type of sound e.g., rat Drinking sound), performance is typically poor. Here we implemented a novel approach to improve such cross-sound modeling (single unit datasets were collected at the auditory midbrain of anesthetized rats). The method had two key features: (a) population responses (e.g., average of 32 units) instead of responses of individual units were analyzed; and (b) the long sound segment was first divided into short segments (single sound-bouts), their similarity was then computed over a new metric involving the response (called Stimulus Response Model map or SRM map), and finally similar sound-bouts (regardless of sound type) and their associated responses (peri-stimulus time histograms, PSTHs) were modelled. Specifically, a committee machine model (artificial neural networks with 20 stratified spectral inputs) was trained with datasets from one sound type before predicting PSTH responses to another sound type. Model performance was markedly improved by up to 92%. Results also suggested the involvement of different neural mechanisms in generating the early and late responses to amplitude transients in the broadband environmental sounds. We concluded that it is possible to perform rather satisfactory cross-sound modeling on datasets grouped together based on their similarities in terms of the new metric of SRM map.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

10602 - Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

Projekt

<a href="/cs/project/GC16-09086J" target="_blank" >GC16-09086J: Zpracování komplexních zvuků v centrálních sluchových jádrech za normálních a patologických podmínek</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2020

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Biosystems

ISSN

0303-2647

e-ISSN

1872-8324

Svazek periodika

187

Číslo periodika v rámci svazku

January

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

8

Strana od-do

—

Kód UT WoS článku

000508746500007

EID výsledku v databázi Scopus

2-s2.0-85073003734