Imidazolium Based Multitopic Guest with 1,3-Adamantylene Centerpiece

Kód výsledku v IS VaVaI

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Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Imidazolium Based Multitopic Guest with 1,3-Adamantylene Centerpiece

Popis výsledku v původním jazyce

Supramolecular host-guest systems involving adamantane derivatives as building units or regulators of an aggregation process have been extensively studied. As adamantane is a lipophilic and round-shaped hydrocarbon, its derivatives fit precisely the interior cavity of b-cyclodextrin (b-CD) and cucurbit[7]uril (CB7) to form water-soluble, highly stable inclusion complexes with the association constants up to 106 m-1 and 1015 m-1, respectively. Accordingly, we designed a novel multitopic guest molecules based on bisimidazolium salts with 1,3-adamantylene centerpiece. Commercial 1,3-adamantanediacetic acid was transformed via sequential esterification, reduction, Appel reaction and quarternization to produce three final guests 1?3 as depicted in Scheme 1.The binding ability of prepared ligands towards b-CD, g-CD, CB7 and CB8, was studied in water solution using NMR and titration calorimetry and in the gas phase using ESI-MS.

Název v anglickém jazyce

Imidazolium Based Multitopic Guest with 1,3-Adamantylene Centerpiece

Popis výsledku anglicky

Supramolecular host-guest systems involving adamantane derivatives as building units or regulators of an aggregation process have been extensively studied. As adamantane is a lipophilic and round-shaped hydrocarbon, its derivatives fit precisely the interior cavity of b-cyclodextrin (b-CD) and cucurbit[7]uril (CB7) to form water-soluble, highly stable inclusion complexes with the association constants up to 106 m-1 and 1015 m-1, respectively. Accordingly, we designed a novel multitopic guest molecules based on bisimidazolium salts with 1,3-adamantylene centerpiece. Commercial 1,3-adamantanediacetic acid was transformed via sequential esterification, reduction, Appel reaction and quarternization to produce three final guests 1?3 as depicted in Scheme 1.The binding ability of prepared ligands towards b-CD, g-CD, CB7 and CB8, was studied in water solution using NMR and titration calorimetry and in the gas phase using ESI-MS.

Druh

O - Ostatní výsledky

CEP obor

CC - Organická chemie

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů