β-Chitin Incorporated and Calcium Carbonate Mineralized Polymeric Hydrogel Scaffolds: An Interesting Bioinspired Biomaterials

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F18%3A63521337" target="_blank" >RIV/70883521:28110/18:63521337 - isvavai.cz</a>

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RIV/70883521:28610/18:63521337

Výsledek na webu

<a href="http://cps.utb.cz/images/aktuality/Sborn%C3%ADk_PLASTKO_2018.pdf" target="_blank" >http://cps.utb.cz/images/aktuality/Sborn%C3%ADk_PLASTKO_2018.pdf</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

β-Chitin Incorporated and Calcium Carbonate Mineralized Polymeric Hydrogel Scaffolds: An Interesting Bioinspired Biomaterials

Popis výsledku v původním jazyce

Polymeric hydrogel scaffolds are interesting as they are considered as potential materials for medicinal usage. “PVP-CMC based hydrogel” or hydrogel scaffolds are one of them. To enhance their bioactivity and preserve biodegradability, β-chitin was incorporated into the PVP-CMC hydrogel. β-chitin is natural polymer isolated from the cuttlebone of common cuttlefish (Sepia officinalis, L.). Both “PVP-CMC” and “PVP-CMC-β-chitin” hydrogels were then mineralized with calcium carbonate (CaCO3) following biomimetic mineralization technique and termed as “PVP-CMC-CaCO3” and “PVP-CMC-β-chitin-CaCO3” to improve bioactivity as well as reinforcement. Rheological data show that incorporation of β-chitin (0.5%) increase the elasticity of all the PVP-CMC based hydrogel scaffolds, while resistance to compression is preserved. The swelling study, conducted in Ringer&apos;s solution at 37°C, indicated that non-mineralized (PVP-CMC and PVP-CMC-β-chitin) hydrogel scaffolds have good water absorption and retention properties in comparison with mineralized (PVP-CMCCaCO3 and PVP-CMC-β-chitin-CaCO3) hydrogel scaffolds. The rheological study confirmed that β-chitin increase the elasticity of PVP-CMC hydrogel scaffold, resulting in an interesting bioinspired biomaterial that has a decent biomedical potential.

Název v anglickém jazyce

β-Chitin Incorporated and Calcium Carbonate Mineralized Polymeric Hydrogel Scaffolds: An Interesting Bioinspired Biomaterials

Popis výsledku anglicky

Polymeric hydrogel scaffolds are interesting as they are considered as potential materials for medicinal usage. “PVP-CMC based hydrogel” or hydrogel scaffolds are one of them. To enhance their bioactivity and preserve biodegradability, β-chitin was incorporated into the PVP-CMC hydrogel. β-chitin is natural polymer isolated from the cuttlebone of common cuttlefish (Sepia officinalis, L.). Both “PVP-CMC” and “PVP-CMC-β-chitin” hydrogels were then mineralized with calcium carbonate (CaCO3) following biomimetic mineralization technique and termed as “PVP-CMC-CaCO3” and “PVP-CMC-β-chitin-CaCO3” to improve bioactivity as well as reinforcement. Rheological data show that incorporation of β-chitin (0.5%) increase the elasticity of all the PVP-CMC based hydrogel scaffolds, while resistance to compression is preserved. The swelling study, conducted in Ringer&apos;s solution at 37°C, indicated that non-mineralized (PVP-CMC and PVP-CMC-β-chitin) hydrogel scaffolds have good water absorption and retention properties in comparison with mineralized (PVP-CMCCaCO3 and PVP-CMC-β-chitin-CaCO3) hydrogel scaffolds. The rheological study confirmed that β-chitin increase the elasticity of PVP-CMC hydrogel scaffold, resulting in an interesting bioinspired biomaterial that has a decent biomedical potential.

Druh

D - Stať ve sborníku

CEP obor

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OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

<a href="/cs/project/LO1504" target="_blank" >LO1504: Centrum polymerních systémů plus</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

Plastko 2018

ISBN

978-80-7454-727-0

ISSN

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e-ISSN

neuvedeno

Počet stran výsledku

6

Strana od-do

201-206

Název nakladatele

Univerzita Tomáše Bati ve Zlíně

Místo vydání

Zlín

Místo konání akce

Zlín

Datum konání akce

18. 4. 2018

Typ akce podle státní příslušnosti

EUR - Evropská akce

Kód UT WoS článku

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