Viscoelastic behavior of mineralized (CaCO3) chitin based PVP-CMC hydrogel scaffolds

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F17%3A63516106" target="_blank" >RIV/70883521:28610/17:63516106 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1063/1.4983001" target="_blank" >http://dx.doi.org/10.1063/1.4983001</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1063/1.4983001" target="_blank" >10.1063/1.4983001</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Viscoelastic behavior of mineralized (CaCO3) chitin based PVP-CMC hydrogel scaffolds

Popis výsledku v původním jazyce

Enhancement of the mechanical as well as functional properties of the perspective mineralized PVP-CMC-CaCO3 hydrogel scaffold applicable for bone tissue engineering is quite essential. Therefore, the incorporation feasibility of chitin, a bioactive, antibacterial and biodegradable material, was examined in order to test its ability to enchance mechanical properties of the PVP-CMC-CaCO3 hydrogel scaffold. Chitin based PVP-CMC hydrogels were prepared and characterized both as non-mineralized and mineralized (CaCO3) form of hydrogel scaffolds. Both α-chitin (commercially bought) and β-chitin (isolated from the cuttlebone) were individually tested. It was observed that at 1% strain all hydrogel scaffolds have linear trend, with highly pronounced elastic properties in comparison to viscous ones. The complex viscosity has directly proportional behavior with negative slope against angular frequency within the range of ω = 0.1 - 100 rad.s-1. Incorporation of β-chitin increased storage modulus of all mineralized samples, making it interesting for further research.

Název v anglickém jazyce

Viscoelastic behavior of mineralized (CaCO3) chitin based PVP-CMC hydrogel scaffolds

Popis výsledku anglicky

Enhancement of the mechanical as well as functional properties of the perspective mineralized PVP-CMC-CaCO3 hydrogel scaffold applicable for bone tissue engineering is quite essential. Therefore, the incorporation feasibility of chitin, a bioactive, antibacterial and biodegradable material, was examined in order to test its ability to enchance mechanical properties of the PVP-CMC-CaCO3 hydrogel scaffold. Chitin based PVP-CMC hydrogels were prepared and characterized both as non-mineralized and mineralized (CaCO3) form of hydrogel scaffolds. Both α-chitin (commercially bought) and β-chitin (isolated from the cuttlebone) were individually tested. It was observed that at 1% strain all hydrogel scaffolds have linear trend, with highly pronounced elastic properties in comparison to viscous ones. The complex viscosity has directly proportional behavior with negative slope against angular frequency within the range of ω = 0.1 - 100 rad.s-1. Incorporation of β-chitin increased storage modulus of all mineralized samples, making it interesting for further research.

Druh

D - Stať ve sborníku

CEP obor

—

OECD FORD obor

10404 - Polymer science

Projekt

<a href="/cs/project/LO1504" target="_blank" >LO1504: Centrum polymerních systémů plus</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2017

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název statě ve sborníku

AIP Conference Proceedings

ISBN

978-0-7354-1513-3

ISSN

0094-243X

e-ISSN

neuvedeno

Počet stran výsledku

7

Strana od-do

1-7

Název nakladatele

American Institute of Physics Publising Inc.

Místo vydání

Melville

Místo konání akce

Zlín

Datum konání akce

26. 7. 2017

Typ akce podle státní příslušnosti

WRD - Celosvětová akce

Kód UT WoS článku

000413481900026