Viscoelastic behavior of Calcium Phosphate Packed Bacterial Cellulose -Polyvinylpyrrolidone based Hydrogel Scaffolds at Human Fever Temperature

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F19%3A63524253" target="_blank" >RIV/70883521:28110/19:63524253 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/70883521:28610/19:63524253

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Viscoelastic behavior of Calcium Phosphate Packed Bacterial Cellulose -Polyvinylpyrrolidone based Hydrogel Scaffolds at Human Fever Temperature

Popis výsledku v původním jazyce

Calcium phosphate (CaP) packed bacterial cellulose (BC) and polyvinylpyrrolidone (PVP) based hydrogel scaffolds (BC-PVPCaP) are being reported here considering its possible application in bone restoration. The primary focus ofthis work is to analyze the viscoe!astic behavior of &apos;BC-PVP-CaP&apos; hydrogel scaffolds at human fever temperature condition (39oC) in swelled state. In BC-PVP scaffolds, CaP is present in the form of P-tricalcium phosphate CP-TCP) and hydroxyapatite (HA) in different concentrations (i.e. P-TCP/HA_20:80, P-TCP/HA_ 40:60, P-TCP/HA_50:50). During evaluation of viscoelasticity, BC-PVP scaffold (without CaP) was marked as a control set. The BC-PVP-CaP 50:50 hydrogel scaffold showed the highest degree of swelling at 39°C among the other BC-PVP-CaP scaffolds. However, the other hydrogel scaffolds were also showed notable viscoelasticity at 39oC. Experimental results confirmed that al! the CaP filled BC-PVP hydrogel scaffolds (BC-PVP-CaP _20:80, BC-PVP-CaP 40:60, BC-PVP-CaP 50:50) exhibit a promising swelling and viscoelastic behavior at human fever temperature condition (39oC), can be endorsed for its potential application in bone repairing /bone restoration.

Název v anglickém jazyce

Viscoelastic behavior of Calcium Phosphate Packed Bacterial Cellulose -Polyvinylpyrrolidone based Hydrogel Scaffolds at Human Fever Temperature

Popis výsledku anglicky

Calcium phosphate (CaP) packed bacterial cellulose (BC) and polyvinylpyrrolidone (PVP) based hydrogel scaffolds (BC-PVPCaP) are being reported here considering its possible application in bone restoration. The primary focus ofthis work is to analyze the viscoe!astic behavior of &apos;BC-PVP-CaP&apos; hydrogel scaffolds at human fever temperature condition (39oC) in swelled state. In BC-PVP scaffolds, CaP is present in the form of P-tricalcium phosphate CP-TCP) and hydroxyapatite (HA) in different concentrations (i.e. P-TCP/HA_20:80, P-TCP/HA_ 40:60, P-TCP/HA_50:50). During evaluation of viscoelasticity, BC-PVP scaffold (without CaP) was marked as a control set. The BC-PVP-CaP 50:50 hydrogel scaffold showed the highest degree of swelling at 39°C among the other BC-PVP-CaP scaffolds. However, the other hydrogel scaffolds were also showed notable viscoelasticity at 39oC. Experimental results confirmed that al! the CaP filled BC-PVP hydrogel scaffolds (BC-PVP-CaP _20:80, BC-PVP-CaP 40:60, BC-PVP-CaP 50:50) exhibit a promising swelling and viscoelastic behavior at human fever temperature condition (39oC), can be endorsed for its potential application in bone repairing /bone restoration.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

20903 - Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

Projekt

<a href="/cs/project/LO1504" target="_blank" >LO1504: Centrum polymerních systémů plus</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2019

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů