Model antimicrobial polymer system based on poly(vinyl chloride) and crystal violet

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28610%2F14%3A43871808" target="_blank" >RIV/70883521:28610/14:43871808 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Model antimicrobial polymer system based on poly(vinyl chloride) and crystal violet

Popis výsledku v původním jazyce

The development of novel antimicrobial materials for biomedical application in indwelling devices such as catheters is very important as the resistance of the pathogens responsible for nosocomial infections towards recent systems has been emerging with an increasing rate. The work presented here is focused on the preparation and characterization of an antimicrobial polymeric system composed of poly(vinyl chloride) in combination with crystal violet as a model compound of organic ionic active species. The antimicrobial activity of the system against gram-negative bacteria Escherichia coli, gram-positive bacteria Staphylococcus aureus and yeasts Candida albicans as the representative microorganisms were evaluated with a disk-diffusion test. The release profile of the active substance was observed with UV-VIS spectrometry. The mechanical properties of the prepared material were tested to verify that they were not altered with respect to the original medical-grade polymer matrix.

Název v anglickém jazyce

Model antimicrobial polymer system based on poly(vinyl chloride) and crystal violet

Popis výsledku anglicky

The development of novel antimicrobial materials for biomedical application in indwelling devices such as catheters is very important as the resistance of the pathogens responsible for nosocomial infections towards recent systems has been emerging with an increasing rate. The work presented here is focused on the preparation and characterization of an antimicrobial polymeric system composed of poly(vinyl chloride) in combination with crystal violet as a model compound of organic ionic active species. The antimicrobial activity of the system against gram-negative bacteria Escherichia coli, gram-positive bacteria Staphylococcus aureus and yeasts Candida albicans as the representative microorganisms were evaluated with a disk-diffusion test. The release profile of the active substance was observed with UV-VIS spectrometry. The mechanical properties of the prepared material were tested to verify that they were not altered with respect to the original medical-grade polymer matrix.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CD - Makromolekulární chemie

OECD FORD obor

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Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Materiali in Tehnologije

ISSN

1580-2949

e-ISSN

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Svazek periodika

48

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

SI - Slovinská republika

Počet stran výsledku

7

Strana od-do

697-703

Kód UT WoS článku

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EID výsledku v databázi Scopus

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