Development of the acoustic startle response in rats and its change after early acoustic trauma

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F71226401%3A_____%2F15%3A%231006180" target="_blank" >RIV/71226401:_____/15:#1006180 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68378041:_____/15:00452413 RIV/00216208:11120/15:43909447

Výsledek na webu

<a href="http://dx.doi.org/10.1016/j.bbr.2015.02.046" target="_blank" >http://dx.doi.org/10.1016/j.bbr.2015.02.046</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.bbr.2015.02.046" target="_blank" >10.1016/j.bbr.2015.02.046</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Development of the acoustic startle response in rats and its change after early acoustic trauma

Popis výsledku v původním jazyce

Even brief acoustic trauma during the critical period of development that results in no permanent hearing threshold shift may lead to altered auditory processing in adulthood. By monitoring the acoustic startle response (ASR), we examined the developmentof auditory function in control rats and in rats exposed to intense noise at the 14th postnatal day (P14). First ASRs appeared on P10?P11 to intense low-frequency tones. By P14, the range of sound intensities and frequencies eliciting ASRs extended considerably, the ASR reactivity being similar at all frequencies (4?32 kHz). During the subsequent two weeks, ASR amplitudes to low-frequency stimuli (4?8 kHz) increased, whereas the ASRs to high-frequency tones were maintained (16 kHz) or even decreased (32 kHz). Compared to controls, noise exposure on P14 (125 dB SPL for 8, 12, or 25 min) produced transient hyper-reactivity to startle stimuli, manifested by a decrease of ASR thresholds and an increase of ASR amplitudes. ASR enhancement oc

Název v anglickém jazyce

Development of the acoustic startle response in rats and its change after early acoustic trauma

Popis výsledku anglicky

Even brief acoustic trauma during the critical period of development that results in no permanent hearing threshold shift may lead to altered auditory processing in adulthood. By monitoring the acoustic startle response (ASR), we examined the developmentof auditory function in control rats and in rats exposed to intense noise at the 14th postnatal day (P14). First ASRs appeared on P10?P11 to intense low-frequency tones. By P14, the range of sound intensities and frequencies eliciting ASRs extended considerably, the ASR reactivity being similar at all frequencies (4?32 kHz). During the subsequent two weeks, ASR amplitudes to low-frequency stimuli (4?8 kHz) increased, whereas the ASRs to high-frequency tones were maintained (16 kHz) or even decreased (32 kHz). Compared to controls, noise exposure on P14 (125 dB SPL for 8, 12, or 25 min) produced transient hyper-reactivity to startle stimuli, manifested by a decrease of ASR thresholds and an increase of ASR amplitudes. ASR enhancement oc

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Behavioural Brain Research

ISSN

0166-4328

e-ISSN

—

Svazek periodika

286

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

10

Strana od-do

212-221

Kód UT WoS článku

000353599600029

EID výsledku v databázi Scopus

2-s2.0-84924714571