Význam rozdílných typů a úrovní antigen-specifické imunity selat při infekci Actinobacillus pleuropneumoniae

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F05%3A06000023" target="_blank" >RIV/00027162:_____/05:06000023 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Significance of different types and levels of antigen-specific immunity to Actinobacillus pleuropneumoniae infection in piglets

Popis výsledku v původním jazyce

We compared the differences in clinical, radiological, pathological changes and cytological findings in blood and bronchoalveolar lavage (BAL) samples between groups of piglets, with different types and levels of antigen-specific immunity afterActinobacillus pleuropneumoniae (App) challenge.Piglets that obtained colostrum-derived antibodies and experienced a low-dose App infection were best protected against App challenge.More apparent clinical and pathol.changes were observed in groupsprotected with either only colostrum-derived antibodies or active immunity induced by a preceding low-dose infection.However, none of the types of protection prevented developing of the disease and characteristic changes in the lungs.Cell counts changesin blood and BAL gave evidence of only bacterial infection in progress; however, between-group differences were not marked.Antibodies (IgG, IgA) present in the respir.tract at the time of challenge played a major role in protection against App infection

Název v anglickém jazyce

Significance of different types and levels of antigen-specific immunity to Actinobacillus pleuropneumoniae infection in piglets

Popis výsledku anglicky

We compared the differences in clinical, radiological, pathological changes and cytological findings in blood and bronchoalveolar lavage (BAL) samples between groups of piglets, with different types and levels of antigen-specific immunity afterActinobacillus pleuropneumoniae (App) challenge.Piglets that obtained colostrum-derived antibodies and experienced a low-dose App infection were best protected against App challenge.More apparent clinical and pathol.changes were observed in groupsprotected with either only colostrum-derived antibodies or active immunity induced by a preceding low-dose infection.However, none of the types of protection prevented developing of the disease and characteristic changes in the lungs.Cell counts changesin blood and BAL gave evidence of only bacterial infection in progress; however, between-group differences were not marked.Antibodies (IgG, IgA) present in the respir.tract at the time of challenge played a major role in protection against App infection

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FN - Epidemiologie, infekční nemoci a klinická imunologie

OECD FORD obor

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Projekt

<a href="/cs/project/GA524%2F01%2F0290" target="_blank" >GA524/01/0290: Charakteristika imunitní odpovědi respiračního traktu prasat na infekci a imunizaci Actinobacillus pleuropneumoniae</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2005

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinární medicína

ISSN

0375-8427

e-ISSN

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Svazek periodika

50

Číslo periodika v rámci svazku

2

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

14

Strana od-do

47-59

Kód UT WoS článku

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EID výsledku v databázi Scopus

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