Stimulace mléčné žlázy skotu vede k zvýšení zastoupení ??-TCR + CD2- lymfocytů

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F06%3A%230000089" target="_blank" >RIV/00027162:_____/06:#0000089 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

??-TCR + CD2- lymphocyte are recruited into bovine mammary gland after stimulation

Popis výsledku v původním jazyce

Gamma delta-TCR lymphocytes were detected in mammary gland lavages collected from 10 clinically healthy virgin heifers before and after udder stimulation with synthetic muramyl dipeptide analogue. Using two-color flow cytometry, CD2+ and CD2- subsets ofgamma delta -TCR lymphocytes were analyzed. CD2+ gamma delta -TCR lymphocytes markedly overnumbered CD2- cells in intact mammary gland. 88.9 percent of gamma delta -TCR were CD2+. After stimulation, neutrophils and gamma delta -TCR lymphocytes were recruited into the mammary gland. Among the gamma delta -TCR lymphocytes, CD2- ones were mainly responsible for their expansion. After stimulation, 60.8 percent of gamma delta -TCR lymphocytes were CD2+ (p lt;0.01 when compared with mammary gland lavages before stimulation). It could be concluded that the cells seem to be involved in the first phase of response to infection affecting mammary gland.

Název v anglickém jazyce

??-TCR + CD2- lymphocyte are recruited into bovine mammary gland after stimulation

Popis výsledku anglicky

Gamma delta-TCR lymphocytes were detected in mammary gland lavages collected from 10 clinically healthy virgin heifers before and after udder stimulation with synthetic muramyl dipeptide analogue. Using two-color flow cytometry, CD2+ and CD2- subsets ofgamma delta -TCR lymphocytes were analyzed. CD2+ gamma delta -TCR lymphocytes markedly overnumbered CD2- cells in intact mammary gland. 88.9 percent of gamma delta -TCR were CD2+. After stimulation, neutrophils and gamma delta -TCR lymphocytes were recruited into the mammary gland. Among the gamma delta -TCR lymphocytes, CD2- ones were mainly responsible for their expansion. After stimulation, 60.8 percent of gamma delta -TCR lymphocytes were CD2+ (p lt;0.01 when compared with mammary gland lavages before stimulation). It could be concluded that the cells seem to be involved in the first phase of response to infection affecting mammary gland.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinární medicína

ISSN

0375-8427

e-ISSN

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Svazek periodika

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Číslo periodika v rámci svazku

5

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

5

Kód UT WoS článku

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EID výsledku v databázi Scopus

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