Charakterizace imunosuprese u králíků po infekci virem myxomatózy

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00027162%3A_____%2F08%3A%230000353" target="_blank" >RIV/00027162:_____/08:#0000353 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Characterisation of immunosuppression in rabbits after infection with myxoma virus

Popis výsledku v původním jazyce

In this study changes in haematological profile, changes in lymphocyte subset distribution and proliferation activity of lymphocytes from different lymphoid compartments on the 2nd, 4th, 6th, 9th and 11th day after experimental infection of rabbits withmyxoma virus was characterised. Haematological changes included moderate leucopenia with significant lymphopenia, neutrophilia, monocytosis and eosinopenia. A decrease of T and increase of CD79alpha+ were observed in draining popliteal lymph node 4 daysafter virus inoculation. From day 6, comparable changes were seen in other lymphoid compartments. From day 9, the mentioned lymphocyte subsets tended to reach their original state in all lymphocyte compartments except draining popliteal lymph node. On the other hand, proliferation activity of lymphocytes was significantly reduced from day 4 until the end of experiment. Presence of virus in respective lymphoid compartments preceded changes in lymphocyte subset distribution or lymphocyte a

Název v anglickém jazyce

Characterisation of immunosuppression in rabbits after infection with myxoma virus

Popis výsledku anglicky

In this study changes in haematological profile, changes in lymphocyte subset distribution and proliferation activity of lymphocytes from different lymphoid compartments on the 2nd, 4th, 6th, 9th and 11th day after experimental infection of rabbits withmyxoma virus was characterised. Haematological changes included moderate leucopenia with significant lymphopenia, neutrophilia, monocytosis and eosinopenia. A decrease of T and increase of CD79alpha+ were observed in draining popliteal lymph node 4 daysafter virus inoculation. From day 6, comparable changes were seen in other lymphoid compartments. From day 9, the mentioned lymphocyte subsets tended to reach their original state in all lymphocyte compartments except draining popliteal lymph node. On the other hand, proliferation activity of lymphocytes was significantly reduced from day 4 until the end of experiment. Presence of virus in respective lymphoid compartments preceded changes in lymphocyte subset distribution or lymphocyte a

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GJ - Choroby a škůdci zvířat, veterinární medicina

OECD FORD obor

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Projekt

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Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)

Rok uplatnění

2008

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Veterinary Microbiology

ISSN

0378-1135

e-ISSN

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Svazek periodika

129

Číslo periodika v rámci svazku

1-2

Stát vydavatele periodika

NL - Nizozemsko

Počet stran výsledku

14

Strana od-do

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Kód UT WoS článku

000255990700012

EID výsledku v databázi Scopus

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