Arteriovenous differences of hematological and coagulation parameters in patients with sepsis

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00064165%3A_____%2F10%3A6515" target="_blank" >RIV/00064165:_____/10:6515 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00216208:11130/10:6330 RIV/00064203:_____/10:6330

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Arteriovenous differences of hematological and coagulation parameters in patients with sepsis

Popis výsledku v původním jazyce

In critically ill patients, arterial or venous blood is available for sampling and measurement of coagulation parameters. The aim of this study was to examine whether in these patients the values of coagulation parameters differ with respect to the source of the blood samples. In patients with severe sepsis, we compared the values of coagulation, thromboelastography and selected hematological parameters between the arterial and venous blood. In most of the investigated parameters (INR, APTT, fibrinogen,erythrocyte, leukocyte and platelet count, hemoglobin level and thromboelastography parameters), we did not find differences (P>0.1). However, we found lower antithrombin activity and higher D-dimer concentration in venous blood compared to arterial blood (P<0.05). It could be associated with increased consumption of antithrombin and generation of D-dimer as a consequence of microthrombi formation in the capillaries. In this case, arterial and venous blood cannot be treated as equivalen

Název v anglickém jazyce

Arteriovenous differences of hematological and coagulation parameters in patients with sepsis

Popis výsledku anglicky

In critically ill patients, arterial or venous blood is available for sampling and measurement of coagulation parameters. The aim of this study was to examine whether in these patients the values of coagulation parameters differ with respect to the source of the blood samples. In patients with severe sepsis, we compared the values of coagulation, thromboelastography and selected hematological parameters between the arterial and venous blood. In most of the investigated parameters (INR, APTT, fibrinogen,erythrocyte, leukocyte and platelet count, hemoglobin level and thromboelastography parameters), we did not find differences (P>0.1). However, we found lower antithrombin activity and higher D-dimer concentration in venous blood compared to arterial blood (P<0.05). It could be associated with increased consumption of antithrombin and generation of D-dimer as a consequence of microthrombi formation in the capillaries. In this case, arterial and venous blood cannot be treated as equivalen

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FD - Onkologie a hematologie

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2010

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Blood coagulation & fibrinolysis

ISSN

0957-5235

e-ISSN

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Svazek periodika

21

Číslo periodika v rámci svazku

8

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

5

Strana od-do

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Kód UT WoS článku

000283718400010

EID výsledku v databázi Scopus

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