Raman spectroscopy at different excitation wavelengths (1064, 785 and 532 nm) as a tool for diagnosis of colon cancer

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11110%2F14%3A10284630" target="_blank" >RIV/00216208:11110/14:10284630 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00064165:_____/14:10284630 RIV/60461373:22340/14:43897261

Výsledek na webu

<a href="http://dx.doi.org/10.1002/jrs.4581" target="_blank" >http://dx.doi.org/10.1002/jrs.4581</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jrs.4581" target="_blank" >10.1002/jrs.4581</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Raman spectroscopy at different excitation wavelengths (1064, 785 and 532 nm) as a tool for diagnosis of colon cancer

Popis výsledku v původním jazyce

Raman spectroscopy is structure sensitive non-destructive method that allows observing the status of biological tissues with minimal impact. This method has a great potential in the diagnosis of various types of degenerative diseases including cancer damages. Near-infrared Fourier transform (NIR-FT)-Raman ((ex) similar to 1064nm), NIR-visible (Vis)-Raman ((ex) similar to 785nm) and Vis-Raman ((ex) similar to 532nm) spectra of normal and colorectal carcinoma colon tissue samples were recorded in macroscopic mode at 10-20 randomly chosen independent sites. In the cases of NIR-Vis- and Vis-Raman spectra, enhanced resonance effects were observed for tissue chromophores absorbing in the visible area. Evident spectral differences were noticed for Raman spectra of normal colon tissue samples in comparison with abnormal samples. The average Raman spectra of colon tissue samples were analysed by principal component analysis (PCA) to discriminate normal and abnormal tissues. PCA of combined data

Název v anglickém jazyce

Raman spectroscopy at different excitation wavelengths (1064, 785 and 532 nm) as a tool for diagnosis of colon cancer

Popis výsledku anglicky

Raman spectroscopy is structure sensitive non-destructive method that allows observing the status of biological tissues with minimal impact. This method has a great potential in the diagnosis of various types of degenerative diseases including cancer damages. Near-infrared Fourier transform (NIR-FT)-Raman ((ex) similar to 1064nm), NIR-visible (Vis)-Raman ((ex) similar to 785nm) and Vis-Raman ((ex) similar to 532nm) spectra of normal and colorectal carcinoma colon tissue samples were recorded in macroscopic mode at 10-20 randomly chosen independent sites. In the cases of NIR-Vis- and Vis-Raman spectra, enhanced resonance effects were observed for tissue chromophores absorbing in the visible area. Evident spectral differences were noticed for Raman spectra of normal colon tissue samples in comparison with abnormal samples. The average Raman spectra of colon tissue samples were analysed by principal component analysis (PCA) to discriminate normal and abnormal tissues. PCA of combined data

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FJ - Chirurgie včetně transplantologie

OECD FORD obor

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Projekt

<a href="/cs/project/NT13259" target="_blank" >NT13259: Význam vyšetřování plasmatických hladin angiogenetických a imunosupresivních faktorů TGF beta1, VEGF a imunitních buněk uplatňujících se v protinádorové odpovědi (NK, CD8) u pacientů s karcinomem tlustého střeva.</a><br>

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2014

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Journal of Raman Spectroscopy

ISSN

0377-0486

e-ISSN

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Svazek periodika

45

Číslo periodika v rámci svazku

10

Stát vydavatele periodika

GB - Spojené království Velké Británie a Severního Irska

Počet stran výsledku

9

Strana od-do

903-911

Kód UT WoS článku

000343762300008

EID výsledku v databázi Scopus

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