Intraoperative Thermography of the Electrical Stimulation Mapping: A Safety Control Study

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11130%2F18%3A10383560" target="_blank" >RIV/00216208:11130/18:10383560 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/68407700:21230/18:00323289 RIV/00064203:_____/18:10383560

Výsledek na webu

<a href="https://doi.org/10.1109/TNSRE.2018.2871875" target="_blank" >https://doi.org/10.1109/TNSRE.2018.2871875</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1109/TNSRE.2018.2871875" target="_blank" >10.1109/TNSRE.2018.2871875</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Intraoperative Thermography of the Electrical Stimulation Mapping: A Safety Control Study

Popis výsledku v původním jazyce

A standard procedure for continuous intra-operative monitoring of the integrity of the corticospinal tracts by eliciting muscle responses is the electric stimulation mapping (ESM). However, standard ESM protocols are ineffective in 20% of young children. We have developed a novel, highly efficient paradigm consisting of short-time burst (30 ms) of high frequency (500 Hz) and high peak current (&lt;= 100 mA), which may cause local tissue overheating. The presented safety control study was therefore designed. The infrared thermography camera captured to-be-resected cortex of 13 patients in vivo during ESM. Thermograms were image processed to reveal discrete ESM thermal effect of currents from 10 to 100 mA. Peak 100 mA currents induced a maximal increase in temperature of 3.1 degrees C, 1.23 +/- 0.72 degrees C in average. The warming correlated with stimulating electrode resistance (p &lt; 0.001). The measurement uncertainty was estimated +/- 1.01 degrees C for the most skeptical conditions. The histopathological evaluation of stimulated tissue (performed in all cases) did not show any destructive changes. Our study demonstrates the ability of the thermographic camera to measure the discrete thermal effect of the ESM. The results provide evidence for the safety of the proposed protocol for full range currents with minimal risk of brain tissue damage.

Název v anglickém jazyce

Intraoperative Thermography of the Electrical Stimulation Mapping: A Safety Control Study

Popis výsledku anglicky

A standard procedure for continuous intra-operative monitoring of the integrity of the corticospinal tracts by eliciting muscle responses is the electric stimulation mapping (ESM). However, standard ESM protocols are ineffective in 20% of young children. We have developed a novel, highly efficient paradigm consisting of short-time burst (30 ms) of high frequency (500 Hz) and high peak current (&lt;= 100 mA), which may cause local tissue overheating. The presented safety control study was therefore designed. The infrared thermography camera captured to-be-resected cortex of 13 patients in vivo during ESM. Thermograms were image processed to reveal discrete ESM thermal effect of currents from 10 to 100 mA. Peak 100 mA currents induced a maximal increase in temperature of 3.1 degrees C, 1.23 +/- 0.72 degrees C in average. The warming correlated with stimulating electrode resistance (p &lt; 0.001). The measurement uncertainty was estimated +/- 1.01 degrees C for the most skeptical conditions. The histopathological evaluation of stimulated tissue (performed in all cases) did not show any destructive changes. Our study demonstrates the ability of the thermographic camera to measure the discrete thermal effect of the ESM. The results provide evidence for the safety of the proposed protocol for full range currents with minimal risk of brain tissue damage.

Druh

J_imp - Článek v periodiku v databázi Web of Science

CEP obor

—

OECD FORD obor

30103 - Neurosciences (including psychophysiology)

Projekt

Výsledek vznikl pri realizaci vícero projektů. Více informací v záložce Projekty.

Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2018

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

IEEE Transactions on Neural Systems and Rehabilitation Engineering

ISSN

1534-4320

e-ISSN

—

Svazek periodika

26

Číslo periodika v rámci svazku

11

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

2126-2133

Kód UT WoS článku

000451250400005

EID výsledku v databázi Scopus

2-s2.0-85054617760