Reduction of renal function during mechanical ventilation of healthy lungs in an animal biomodel

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11140%2F15%3A10227309" target="_blank" >RIV/00216208:11140/15:10227309 - isvavai.cz</a>

Nalezeny alternativní kódy

RIV/00669806:_____/15:10227309

Výsledek na webu

<a href="http://www.elis.sk/download_file.php?product_id=4112&session_id=3hr2qerk9ltfgoe8tc3cad40f0" target="_blank" >http://www.elis.sk/download_file.php?product_id=4112&session_id=3hr2qerk9ltfgoe8tc3cad40f0</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4149/BLL_2015_005" target="_blank" >10.4149/BLL_2015_005</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Reduction of renal function during mechanical ventilation of healthy lungs in an animal biomodel

Popis výsledku v původním jazyce

Objectives: To identify factors involved in reno-pulmonary interactions during mechanical ventilation of helthy lungs. Materials and Methods: The study included a total of 25 healthy domestic piglets with an average weight of 22.7kg (SD 2.17). The animals were divided into three groups based on different strategies of ventilation: Group A (n=5); spontaneously breathing piglets; group B (n=10) the animals ventilated 12 hours with tidal volume of 6ml.kg-1 and group C (n=10) with animals ventilated 12 hours with tidal volume 10ml.kg-1. Clinical monitoring , as well as laboratory tests, were performed for all groups at baseline and then at 1 hour and 12 hours for groups B and C. Ventilation indices, systemic blood pressure, urine output, laboratory analysis of urine and serum, creatinine clearance, glomerular filtration index, fractional excretion of sodium, free water clearance, u-K/u-Na ratio and tissue samples were recorded. The data obtained were statistically analysed and values havin

Název v anglickém jazyce

Reduction of renal function during mechanical ventilation of healthy lungs in an animal biomodel

Popis výsledku anglicky

Objectives: To identify factors involved in reno-pulmonary interactions during mechanical ventilation of helthy lungs. Materials and Methods: The study included a total of 25 healthy domestic piglets with an average weight of 22.7kg (SD 2.17). The animals were divided into three groups based on different strategies of ventilation: Group A (n=5); spontaneously breathing piglets; group B (n=10) the animals ventilated 12 hours with tidal volume of 6ml.kg-1 and group C (n=10) with animals ventilated 12 hours with tidal volume 10ml.kg-1. Clinical monitoring , as well as laboratory tests, were performed for all groups at baseline and then at 1 hour and 12 hours for groups B and C. Ventilation indices, systemic blood pressure, urine output, laboratory analysis of urine and serum, creatinine clearance, glomerular filtration index, fractional excretion of sodium, free water clearance, u-K/u-Na ratio and tissue samples were recorded. The data obtained were statistically analysed and values havin

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FG - Pediatrie

OECD FORD obor

—

Projekt

—

Návaznosti

Z - Vyzkumny zamer (s odkazem do CEZ)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Bratislavské lekárske listy

ISSN

0006-9248

e-ISSN

—

Svazek periodika

116

Číslo periodika v rámci svazku

1

Stát vydavatele periodika

SK - Slovenská republika

Počet stran výsledku

5

Strana od-do

25-29

Kód UT WoS článku

000349275900005

EID výsledku v databázi Scopus

2-s2.0-84921326575