Determination of the correct migration time and other parameters of the Haarhoff-van der Linde function from the peak geometry characteristics

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216208%3A11310%2F15%3A10294249" target="_blank" >RIV/00216208:11310/15:10294249 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1002/elps.201400463" target="_blank" >http://dx.doi.org/10.1002/elps.201400463</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/elps.201400463" target="_blank" >10.1002/elps.201400463</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Determination of the correct migration time and other parameters of the Haarhoff-van der Linde function from the peak geometry characteristics

Popis výsledku v původním jazyce

For Gaussian peaks, the migration time of the analyte results as the position of the top of the peak and the zone variance is proportional to the peak width. Similar relations have not yet been derived for the Haarhoff-van der Linde (HVL) function, whichappears as a fundamental peak-shape function in electrophoresis. We derive the relations between the geometrical measures of the HVL-shaped peak, that is the position of its maximum, its width and a measure of its asymmetry, and the respective parameters a(1), a(2), and a(3), of the corresponding HVL function. Under the condition of the HVL-shaped peak, the a(1) parameter reflects the true migration time of the analyte, which may differ from the peak top position significantly. Our procedure allows usto express the parameters without the need of any external data processing (nonlinear regression). We demonstrate our approach on simulated peaks and on experimental data integrated by the ChemStation software (delivered with the CE instr

Název v anglickém jazyce

Determination of the correct migration time and other parameters of the Haarhoff-van der Linde function from the peak geometry characteristics

Popis výsledku anglicky

For Gaussian peaks, the migration time of the analyte results as the position of the top of the peak and the zone variance is proportional to the peak width. Similar relations have not yet been derived for the Haarhoff-van der Linde (HVL) function, whichappears as a fundamental peak-shape function in electrophoresis. We derive the relations between the geometrical measures of the HVL-shaped peak, that is the position of its maximum, its width and a measure of its asymmetry, and the respective parameters a(1), a(2), and a(3), of the corresponding HVL function. Under the condition of the HVL-shaped peak, the a(1) parameter reflects the true migration time of the analyte, which may differ from the peak top position significantly. Our procedure allows usto express the parameters without the need of any external data processing (nonlinear regression). We demonstrate our approach on simulated peaks and on experimental data integrated by the ChemStation software (delivered with the CE instr

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

CB - Analytická chemie, separace

OECD FORD obor

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Projekt

<a href="/cs/project/GPP206%2F12%2FP630" target="_blank" >GPP206/12/P630: Sjednocený model (dynamické) chirální separace v kapilární zónové elektroforéze a integrované softwarové řešení</a><br>

Návaznosti

S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Electrophoresis

ISSN

0173-0835

e-ISSN

—

Svazek periodika

36

Číslo periodika v rámci svazku

5

Stát vydavatele periodika

DE - Spolková republika Německo

Počet stran výsledku

7

Strana od-do

655-661

Kód UT WoS článku

000350547400005

EID výsledku v databázi Scopus

2-s2.0-84923822134