Exercise End-Tidal CO2 Predicts Central Sleep Apnea in Patients With Heart Failure

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14110%2F15%3A00082715" target="_blank" >RIV/00216224:14110/15:00082715 - isvavai.cz</a>

Výsledek na webu

<a href="http://dx.doi.org/10.1378/chest.14-2114" target="_blank" >http://dx.doi.org/10.1378/chest.14-2114</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1378/chest.14-2114" target="_blank" >10.1378/chest.14-2114</a>

Jazyk výsledku

angličtina

Název v původním jazyce

Exercise End-Tidal CO2 Predicts Central Sleep Apnea in Patients With Heart Failure

Popis výsledku v původním jazyce

BACKGROUND: Increased CO2 chemosensitivity and augmented exercise ventilation are characteristic of patients with heart failure (HF) with central sleep apnea (CSA). The aim of this study was to test the hypothesis that decreased end-tidal CO2 by cardiopulmonary exercise testing predicts CSA in patients with HF. METHODS: Consecutive ambulatory patients with New York Heart Association II to III HF were prospectively evaluated by CO2 chemosensitivity by rebreathe, cardiopulmonary exercise testing, and polysomnography (PSG). Subjects were classified as having either CSA (n = 20) or no sleep apnea (n = 13) by PSG; a central apnea-hypopnea index (AHI) &gt;= 5 was used to define CSA. Subgroups were compared by t test or Mann-Whitney test and data summarized as mean +/- SD. P &lt; .05 was considered significant. RESULTS: At rest, subjects with CSA had higher central CO2 chemosensitivity (Delta minute ventilation [(V) over dotE]/Delta partial pressure of end-tidal CO2 [PETCO2], 2.3 +/- 1.0 L/mi

Název v anglickém jazyce

Exercise End-Tidal CO2 Predicts Central Sleep Apnea in Patients With Heart Failure

Popis výsledku anglicky

BACKGROUND: Increased CO2 chemosensitivity and augmented exercise ventilation are characteristic of patients with heart failure (HF) with central sleep apnea (CSA). The aim of this study was to test the hypothesis that decreased end-tidal CO2 by cardiopulmonary exercise testing predicts CSA in patients with HF. METHODS: Consecutive ambulatory patients with New York Heart Association II to III HF were prospectively evaluated by CO2 chemosensitivity by rebreathe, cardiopulmonary exercise testing, and polysomnography (PSG). Subjects were classified as having either CSA (n = 20) or no sleep apnea (n = 13) by PSG; a central apnea-hypopnea index (AHI) &gt;= 5 was used to define CSA. Subgroups were compared by t test or Mann-Whitney test and data summarized as mean +/- SD. P &lt; .05 was considered significant. RESULTS: At rest, subjects with CSA had higher central CO2 chemosensitivity (Delta minute ventilation [(V) over dotE]/Delta partial pressure of end-tidal CO2 [PETCO2], 2.3 +/- 1.0 L/mi

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FE - Ostatní obory vnitřního lékařství

OECD FORD obor

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Projekt

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Návaznosti

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Rok uplatnění

2015

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

CHEST

ISSN

0012-3692

e-ISSN

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Svazek periodika

147

Číslo periodika v rámci svazku

6

Stát vydavatele periodika

US - Spojené státy americké

Počet stran výsledku

8

Strana od-do

1566-1573

Kód UT WoS článku

000355837900037

EID výsledku v databázi Scopus

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