Chemoprotective effects of broccoli juice treated with high presssure

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14510%2F06%3A00031474" target="_blank" >RIV/00216224:14510/06:00031474 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Chemoprotective effects of broccoli juice treated with high presssure

Popis výsledku v původním jazyce

We investigated chemoprotective effects of broccoli juice, treated by high pressure method, using 500 MPa for a period of 10 minutes. By the use of this method, the conservation of nutritionally important substances occurs (for example vitamins, polyphenolic compounds, glucosinolates and other constituent substances). We followed the inhibition of mutagenicity of the model mutagen, N-nitroso-N-methylurea (MNU) by means of in vivo micronucleus test. After fourteen-days application of broccoli juice (0.2ml/10 g of body weight of mouse) and after single administration of MNU mutagen (50 mg/kg), a statistically significant decrease (p&lt;0.01) occured, of number of micronuclei induced by the application of MNU. Broccoli juice treated by high pressure, therefore seems to have a preventive potential against MNU-induced micronuclei formation in BALB/C mouse bone marrow cells.

Název v anglickém jazyce

Chemoprotective effects of broccoli juice treated with high presssure

Popis výsledku anglicky

We investigated chemoprotective effects of broccoli juice, treated by high pressure method, using 500 MPa for a period of 10 minutes. By the use of this method, the conservation of nutritionally important substances occurs (for example vitamins, polyphenolic compounds, glucosinolates and other constituent substances). We followed the inhibition of mutagenicity of the model mutagen, N-nitroso-N-methylurea (MNU) by means of in vivo micronucleus test. After fourteen-days application of broccoli juice (0.2ml/10 g of body weight of mouse) and after single administration of MNU mutagen (50 mg/kg), a statistically significant decrease (p&lt;0.01) occured, of number of micronuclei induced by the application of MNU. Broccoli juice treated by high pressure, therefore seems to have a preventive potential against MNU-induced micronuclei formation in BALB/C mouse bone marrow cells.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

GM - Potravinářství

OECD FORD obor

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Projekt

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Návaznosti

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Rok uplatnění

2006

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

Czech J. Food Sci.

ISSN

1212-1800

e-ISSN

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Svazek periodika

roč. 24

Číslo periodika v rámci svazku

č. 1

Stát vydavatele periodika

CZ - Česká republika

Počet stran výsledku

7

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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