Broccoli juice treated by high presssure: chemoprotective effects of sulforaphane and indole-3-carbinol

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14510%2F07%3A00031920" target="_blank" >RIV/00216224:14510/07:00031920 - isvavai.cz</a>

Výsledek na webu

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DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Broccoli juice treated by high presssure: chemoprotective effects of sulforaphane and indole-3-carbinol

Popis výsledku v původním jazyce

Numerous animal and epidemiological studies have demonstrated that consumption of cruciferous vegetables is inversely correlated with the cancer incidence. Using the shortterm mutagenicity test in vivo micronucleus test, we investigated inhibition of mutagenicity of IQ and MNU by influence of broccoli juice treated by high pressure method, 500 MPa for a period of 10 minutes. This technique of treatment suppresses the growth of microorganisms at simultaneous conservation of nutritionally important substances (vitamins, polyphenols, glucosinolates). We also investigated anticlastogenic aktivity of sulforaphane (SFN) and indol3carbinol (I3C). These two substances are found in inactive form (glucosinolates) in cruciferous vegetables Fourteendays application of broccoli juice and threedays application of I3C and SFN led to statistically significant inhibition of mutagenity.

Název v anglickém jazyce

Broccoli juice treated by high presssure: chemoprotective effects of sulforaphane and indole-3-carbinol

Popis výsledku anglicky

Numerous animal and epidemiological studies have demonstrated that consumption of cruciferous vegetables is inversely correlated with the cancer incidence. Using the shortterm mutagenicity test in vivo micronucleus test, we investigated inhibition of mutagenicity of IQ and MNU by influence of broccoli juice treated by high pressure method, 500 MPa for a period of 10 minutes. This technique of treatment suppresses the growth of microorganisms at simultaneous conservation of nutritionally important substances (vitamins, polyphenols, glucosinolates). We also investigated anticlastogenic aktivity of sulforaphane (SFN) and indol3carbinol (I3C). These two substances are found in inactive form (glucosinolates) in cruciferous vegetables Fourteendays application of broccoli juice and threedays application of I3C and SFN led to statistically significant inhibition of mutagenity.

Druh

J_x - Nezařazeno - Článek v odborném periodiku (Jimp, Jsc a Jost)

CEP obor

FB - Endokrinologie, diabetologie, metabolismus, výživa

OECD FORD obor

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Projekt

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Návaznosti

S - Specificky vyzkum na vysokych skolach

Rok uplatnění

2007

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Název periodika

High pressure research

ISSN

0895-7959

e-ISSN

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Svazek periodika

vol. 27

Číslo periodika v rámci svazku

n. 1

Stát vydavatele periodika

FR - Francouzská republika

Počet stran výsledku

6

Strana od-do

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Kód UT WoS článku

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EID výsledku v databázi Scopus

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